miR-29b inhibits TGF-β1-induced cell proliferation in articular chondrocytes

miR-29b inhibits TGF-β1-induced cell proliferation in articular chondrocytes

Transforming growth factor β1 (TGF-β1) is a known regulator of chondrocyte proliferation and promotes cartilage repair in osteoarthritis (OA). microRNA-29b-3p (miR-29b-3p) is downregulated by TGF-β1 and overexpressed in OA cartilage. However, the ability of miR-29b-3p to mediate the chondrocyte pro-...

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Bibliographic Details
Main Authors: Masahiro Horita, Shun-Neng Hsu, Anna Raper, Colin Farquharson, Louise A. Stephen
Format: Article
Language:English
Published: Elsevier 2022-03-01
Series:Biochemistry and Biophysics Reports
Subjects:
Chondrocyte
TGF-β1
microRNA-29b-3p
Osteoarthritis
Cell proliferation
Online Access:http://www.sciencedirect.com/science/article/pii/S2405580822000176

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