Physiological problems in patients undergoing autologous and allogeneic hematopoietic stem cell transplantation

Objective: Stem cell transplantation is usually performed in an effort to extend the patient′s life span and to improve their quality of life. This study was conducted to determine the postoperative physiological effects experienced by patients who had undergone autologous and allogeneic stem cell t...

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Main Authors: Sevgisun Kapucu, Yasemin Karacan
Format: Article
Language:English
Published: Elsevier 2014-01-01
Series:Asia-Pacific Journal of Oncology Nursing
Subjects:
Online Access:http://www.apjon.org/article.asp?issn=2347-5625;year=2014;volume=1;issue=1;spage=50;epage=54;aulast=
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author Sevgisun Kapucu
Yasemin Karacan
author_facet Sevgisun Kapucu
Yasemin Karacan
author_sort Sevgisun Kapucu
collection DOAJ
description Objective: Stem cell transplantation is usually performed in an effort to extend the patient′s life span and to improve their quality of life. This study was conducted to determine the postoperative physiological effects experienced by patients who had undergone autologous and allogeneic stem cell transplantation. Methods: The research is a descriptive study conducted with a sample of 60 patients at Stem Cell Transplantation Units in Ankara. Percentile calculation and chi-square tests were used to evaluate the data. Results: When a comparison was made between patients who had undergone allogeneic Hematopoietic stem cell transplantation (HSCT) and those who had undergone autologous HSCT, results indicated that problems occurred more often for the allogeneic HSCT patients. The problems included: Digestion (94.3%), dermatological (76.7%), cardiac and respiratory (66.7%), neurological (66.7%), eye (56.7%), infections (26.7%) and Graft Versus Host Disease (5 patients). Furthermore, the problems with pain (50%), numbness and tingling (40%), and speech disorders (3 patients) were observed more often in autologous BMT patients. Conclusion: Autologous and allogeneic patients experienced most of physical problems due to they receive high doses of chemotherapy. Therefore, it is recommended that an interdisciplinary support team approach should be usedtohelp reduce and manage the problems that may arise during patient care.
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spelling doaj.art-426fd7deee024889943bf94f08dddb8b2023-08-02T01:21:11ZengElsevierAsia-Pacific Journal of Oncology Nursing2347-56252014-01-0111505410.4103/2347-5625.135821Physiological problems in patients undergoing autologous and allogeneic hematopoietic stem cell transplantationSevgisun KapucuYasemin KaracanObjective: Stem cell transplantation is usually performed in an effort to extend the patient′s life span and to improve their quality of life. This study was conducted to determine the postoperative physiological effects experienced by patients who had undergone autologous and allogeneic stem cell transplantation. Methods: The research is a descriptive study conducted with a sample of 60 patients at Stem Cell Transplantation Units in Ankara. Percentile calculation and chi-square tests were used to evaluate the data. Results: When a comparison was made between patients who had undergone allogeneic Hematopoietic stem cell transplantation (HSCT) and those who had undergone autologous HSCT, results indicated that problems occurred more often for the allogeneic HSCT patients. The problems included: Digestion (94.3%), dermatological (76.7%), cardiac and respiratory (66.7%), neurological (66.7%), eye (56.7%), infections (26.7%) and Graft Versus Host Disease (5 patients). Furthermore, the problems with pain (50%), numbness and tingling (40%), and speech disorders (3 patients) were observed more often in autologous BMT patients. Conclusion: Autologous and allogeneic patients experienced most of physical problems due to they receive high doses of chemotherapy. Therefore, it is recommended that an interdisciplinary support team approach should be usedtohelp reduce and manage the problems that may arise during patient care.http://www.apjon.org/article.asp?issn=2347-5625;year=2014;volume=1;issue=1;spage=50;epage=54;aulast=Autologousallogeneichematopoietic stem celltransplantationphysiological problems
spellingShingle Sevgisun Kapucu
Yasemin Karacan
Physiological problems in patients undergoing autologous and allogeneic hematopoietic stem cell transplantation
Asia-Pacific Journal of Oncology Nursing
Autologous
allogeneic
hematopoietic stem cell
transplantation
physiological problems
title Physiological problems in patients undergoing autologous and allogeneic hematopoietic stem cell transplantation
title_full Physiological problems in patients undergoing autologous and allogeneic hematopoietic stem cell transplantation
title_fullStr Physiological problems in patients undergoing autologous and allogeneic hematopoietic stem cell transplantation
title_full_unstemmed Physiological problems in patients undergoing autologous and allogeneic hematopoietic stem cell transplantation
title_short Physiological problems in patients undergoing autologous and allogeneic hematopoietic stem cell transplantation
title_sort physiological problems in patients undergoing autologous and allogeneic hematopoietic stem cell transplantation
topic Autologous
allogeneic
hematopoietic stem cell
transplantation
physiological problems
url http://www.apjon.org/article.asp?issn=2347-5625;year=2014;volume=1;issue=1;spage=50;epage=54;aulast=
work_keys_str_mv AT sevgisunkapucu physiologicalproblemsinpatientsundergoingautologousandallogeneichematopoieticstemcelltransplantation
AT yaseminkaracan physiologicalproblemsinpatientsundergoingautologousandallogeneichematopoieticstemcelltransplantation