Xylitol inhibits J774A.1 macrophage adhesion in vitro
The aim of this work was to evaluate the effect of xylitol on J774A.1 macrophage adhesion. Adhesion consisted of a three-hour interval, at room temperature, followed by washing and cell incubation at 37ºC/5% CO2/ 48h. Xylitol was used to treat the cells either before (for 24h) or after the cell incu...
| Main Authors: | , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Instituto de Tecnologia do Paraná (Tecpar)
2011-12-01
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| Series: | Brazilian Archives of Biology and Technology |
| Subjects: | |
| Online Access: | http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1516-89132011000600017 |
| _version_ | 1811227333743345664 |
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| author | Aline Siqueira Ferreira Maria Aparecida de Souza Nádia Rezende Barbosa Raposo Ana Paula Ferreira Silvio Silvério da Silva |
| author_facet | Aline Siqueira Ferreira Maria Aparecida de Souza Nádia Rezende Barbosa Raposo Ana Paula Ferreira Silvio Silvério da Silva |
| author_sort | Aline Siqueira Ferreira |
| collection | DOAJ |
| description | The aim of this work was to evaluate the effect of xylitol on J774A.1 macrophage adhesion. Adhesion consisted of a three-hour interval, at room temperature, followed by washing and cell incubation at 37ºC/5% CO2/ 48h. Xylitol was used to treat the cells either before (for 24h) or after the cell incubation (for 48h) at 5% as final concentration in both the situations. It was found that xylitol was effective in preventing the adhesion in both the conditions in spite of the former being 100-fold greater and significant (p < 0.001). The results pointed to an important xylitol action on macrophage adhesion, which should be further investigated as an inflammatory control. |
| first_indexed | 2024-04-12T09:40:54Z |
| format | Article |
| id | doaj.art-4270bd460e084edb916e26bb333c6cfd |
| institution | Directory Open Access Journal |
| issn | 1516-8913 1678-4324 |
| language | English |
| last_indexed | 2024-04-12T09:40:54Z |
| publishDate | 2011-12-01 |
| publisher | Instituto de Tecnologia do Paraná (Tecpar) |
| record_format | Article |
| series | Brazilian Archives of Biology and Technology |
| spelling | doaj.art-4270bd460e084edb916e26bb333c6cfd2022-12-22T03:38:04ZengInstituto de Tecnologia do Paraná (Tecpar)Brazilian Archives of Biology and Technology1516-89131678-43242011-12-015461211121610.1590/S1516-89132011000600017Xylitol inhibits J774A.1 macrophage adhesion in vitroAline Siqueira FerreiraMaria Aparecida de SouzaNádia Rezende Barbosa RaposoAna Paula FerreiraSilvio Silvério da SilvaThe aim of this work was to evaluate the effect of xylitol on J774A.1 macrophage adhesion. Adhesion consisted of a three-hour interval, at room temperature, followed by washing and cell incubation at 37ºC/5% CO2/ 48h. Xylitol was used to treat the cells either before (for 24h) or after the cell incubation (for 48h) at 5% as final concentration in both the situations. It was found that xylitol was effective in preventing the adhesion in both the conditions in spite of the former being 100-fold greater and significant (p < 0.001). The results pointed to an important xylitol action on macrophage adhesion, which should be further investigated as an inflammatory control.http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1516-89132011000600017adhesionJ774A1 macrophagesxylitol |
| spellingShingle | Aline Siqueira Ferreira Maria Aparecida de Souza Nádia Rezende Barbosa Raposo Ana Paula Ferreira Silvio Silvério da Silva Xylitol inhibits J774A.1 macrophage adhesion in vitro Brazilian Archives of Biology and Technology adhesion J774A 1 macrophages xylitol |
| title | Xylitol inhibits J774A.1 macrophage adhesion in vitro |
| title_full | Xylitol inhibits J774A.1 macrophage adhesion in vitro |
| title_fullStr | Xylitol inhibits J774A.1 macrophage adhesion in vitro |
| title_full_unstemmed | Xylitol inhibits J774A.1 macrophage adhesion in vitro |
| title_short | Xylitol inhibits J774A.1 macrophage adhesion in vitro |
| title_sort | xylitol inhibits j774a 1 macrophage adhesion in vitro |
| topic | adhesion J774A 1 macrophages xylitol |
| url | http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1516-89132011000600017 |
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