Mis-Genotyping of Some Hepatitis D Virus Genotype 2 and 5 Sequences Using HDVdb
Evidence that Hepatitis D virus (HDV) genotype is involved in HDV infection pathogenesis is increasing. Indeed, HDV genotypes have been shown to be linked to different outcomes in terms of liver fibrosis and treatment response. Herein, we show that the promising HDVdb genotyping tool available onlin...
| Main Authors: | , , , |
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| Format: | Article |
| Language: | English |
| Published: |
MDPI AG
2020-09-01
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| Series: | Viruses |
| Subjects: | |
| Online Access: | https://www.mdpi.com/1999-4915/12/10/1066 |
| _version_ | 1827705545796091904 |
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| author | Caroline Charre Frédéric le Gal Paul Dény Caroline Scholtès |
| author_facet | Caroline Charre Frédéric le Gal Paul Dény Caroline Scholtès |
| author_sort | Caroline Charre |
| collection | DOAJ |
| description | Evidence that Hepatitis D virus (HDV) genotype is involved in HDV infection pathogenesis is increasing. Indeed, HDV genotypes have been shown to be linked to different outcomes in terms of liver fibrosis and treatment response. Herein, we show that the promising HDVdb genotyping tool available online can lead to wrong genotyping results. The current HDVdb algorithm should be carefully considered as a “beta-version” and warrants algorithm core corrections, as soon as possible, for an optimal and beneficial use. |
| first_indexed | 2024-03-10T16:06:30Z |
| format | Article |
| id | doaj.art-4270e5c6e4b64462b7aa272593f9a263 |
| institution | Directory Open Access Journal |
| issn | 1999-4915 |
| language | English |
| last_indexed | 2024-03-10T16:06:30Z |
| publishDate | 2020-09-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Viruses |
| spelling | doaj.art-4270e5c6e4b64462b7aa272593f9a2632023-11-20T14:51:14ZengMDPI AGViruses1999-49152020-09-011210106610.3390/v12101066Mis-Genotyping of Some Hepatitis D Virus Genotype 2 and 5 Sequences Using HDVdbCaroline Charre0Frédéric le Gal1Paul Dény2Caroline Scholtès3University Claude Bernard Lyon 1 (UCBL1), University of Lyon, 69008 Lyon, FranceLaboratoire de Microbiologie Clinique, Hôpitaux Universitaires de Paris Seine Saint-Denis, Site Avicenne, Université Sorbonne Paris Cité, 93022 Bobigny, FranceUniversity Claude Bernard Lyon 1 (UCBL1), University of Lyon, 69008 Lyon, FranceUniversity Claude Bernard Lyon 1 (UCBL1), University of Lyon, 69008 Lyon, FranceEvidence that Hepatitis D virus (HDV) genotype is involved in HDV infection pathogenesis is increasing. Indeed, HDV genotypes have been shown to be linked to different outcomes in terms of liver fibrosis and treatment response. Herein, we show that the promising HDVdb genotyping tool available online can lead to wrong genotyping results. The current HDVdb algorithm should be carefully considered as a “beta-version” and warrants algorithm core corrections, as soon as possible, for an optimal and beneficial use.https://www.mdpi.com/1999-4915/12/10/1066hepatitis delta virusdatabasegenotypingwebservererrorsmis-genotyping |
| spellingShingle | Caroline Charre Frédéric le Gal Paul Dény Caroline Scholtès Mis-Genotyping of Some Hepatitis D Virus Genotype 2 and 5 Sequences Using HDVdb Viruses hepatitis delta virus database genotyping webserver errors mis-genotyping |
| title | Mis-Genotyping of Some Hepatitis D Virus Genotype 2 and 5 Sequences Using HDVdb |
| title_full | Mis-Genotyping of Some Hepatitis D Virus Genotype 2 and 5 Sequences Using HDVdb |
| title_fullStr | Mis-Genotyping of Some Hepatitis D Virus Genotype 2 and 5 Sequences Using HDVdb |
| title_full_unstemmed | Mis-Genotyping of Some Hepatitis D Virus Genotype 2 and 5 Sequences Using HDVdb |
| title_short | Mis-Genotyping of Some Hepatitis D Virus Genotype 2 and 5 Sequences Using HDVdb |
| title_sort | mis genotyping of some hepatitis d virus genotype 2 and 5 sequences using hdvdb |
| topic | hepatitis delta virus database genotyping webserver errors mis-genotyping |
| url | https://www.mdpi.com/1999-4915/12/10/1066 |
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