Pleomorphic xanthomas: A clue to rare familial hypercholesterolemia
Xanthomas are the subcutaneous lipid deposits which can be seen in normolipedemic or hyperlipidemic conditions. Xanathomas are usually of single type and presence of polymorphic xanthomas arise suspicion of dyslipidemia. We report a case of young girl presenting with pleomorphic xanthomas (Xanthelas...
| Main Authors: | , , |
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| Format: | Article |
| Language: | English |
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Wolters Kluwer Medknow Publications
2021-01-01
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| Series: | Clinical Dermatology Review |
| Subjects: | |
| Online Access: | http://www.cdriadvlkn.org/article.asp?issn=2542-551X;year=2021;volume=5;issue=2;spage=229;epage=232;aulast=Singh |
| _version_ | 1818736326872137728 |
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| author | Shivangi Singh Pankaj Kumar Tiwary Anupama Singh |
| author_facet | Shivangi Singh Pankaj Kumar Tiwary Anupama Singh |
| author_sort | Shivangi Singh |
| collection | DOAJ |
| description | Xanthomas are the subcutaneous lipid deposits which can be seen in normolipedemic or hyperlipidemic conditions. Xanathomas are usually of single type and presence of polymorphic xanthomas arise suspicion of dyslipidemia. We report a case of young girl presenting with pleomorphic xanthomas (Xanthelasma palpebrarum, intertriginous Xanthomas, tendon Xanthomas, and eruptive xanthomas), hypothyroidism and multiple cardiac valvular involvements with very high serum total cholesterol and low-density lipoprotein along with deranged lipid profile in both parents. Pleomorphic xanthoma arouses a suspicion and helped in making a diagnosis of rare homozygous familial hypercholesterolemia. |
| first_indexed | 2024-12-18T00:35:23Z |
| format | Article |
| id | doaj.art-4271e668cfe647ec8bb992ad0cb057d6 |
| institution | Directory Open Access Journal |
| issn | 2542-551X 2542-5528 |
| language | English |
| last_indexed | 2024-12-18T00:35:23Z |
| publishDate | 2021-01-01 |
| publisher | Wolters Kluwer Medknow Publications |
| record_format | Article |
| series | Clinical Dermatology Review |
| spelling | doaj.art-4271e668cfe647ec8bb992ad0cb057d62022-12-21T21:27:01ZengWolters Kluwer Medknow PublicationsClinical Dermatology Review2542-551X2542-55282021-01-015222923210.4103/CDR.CDR_73_20Pleomorphic xanthomas: A clue to rare familial hypercholesterolemiaShivangi SinghPankaj Kumar TiwaryAnupama SinghXanthomas are the subcutaneous lipid deposits which can be seen in normolipedemic or hyperlipidemic conditions. Xanathomas are usually of single type and presence of polymorphic xanthomas arise suspicion of dyslipidemia. We report a case of young girl presenting with pleomorphic xanthomas (Xanthelasma palpebrarum, intertriginous Xanthomas, tendon Xanthomas, and eruptive xanthomas), hypothyroidism and multiple cardiac valvular involvements with very high serum total cholesterol and low-density lipoprotein along with deranged lipid profile in both parents. Pleomorphic xanthoma arouses a suspicion and helped in making a diagnosis of rare homozygous familial hypercholesterolemia.http://www.cdriadvlkn.org/article.asp?issn=2542-551X;year=2021;volume=5;issue=2;spage=229;epage=232;aulast=Singhhypercholesterolemiaintertriginous xanthomapleomorphic xanthoma |
| spellingShingle | Shivangi Singh Pankaj Kumar Tiwary Anupama Singh Pleomorphic xanthomas: A clue to rare familial hypercholesterolemia Clinical Dermatology Review hypercholesterolemia intertriginous xanthoma pleomorphic xanthoma |
| title | Pleomorphic xanthomas: A clue to rare familial hypercholesterolemia |
| title_full | Pleomorphic xanthomas: A clue to rare familial hypercholesterolemia |
| title_fullStr | Pleomorphic xanthomas: A clue to rare familial hypercholesterolemia |
| title_full_unstemmed | Pleomorphic xanthomas: A clue to rare familial hypercholesterolemia |
| title_short | Pleomorphic xanthomas: A clue to rare familial hypercholesterolemia |
| title_sort | pleomorphic xanthomas a clue to rare familial hypercholesterolemia |
| topic | hypercholesterolemia intertriginous xanthoma pleomorphic xanthoma |
| url | http://www.cdriadvlkn.org/article.asp?issn=2542-551X;year=2021;volume=5;issue=2;spage=229;epage=232;aulast=Singh |
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