How Do mAbs Make Use of Complement to Kill Cancer Cells? The Role of Ca<sup>2+</sup>
We examined the kinetics and mechanisms by which monoclonal antibodies (mAbs) utilize complement to rapidly kill targeted cancer cells. Based on results from flow cytometry, confocal microscopy and high-resolution digital imaging experiments, the general patterns which have emerged reveal cytotoxic...
Main Authors: | , |
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Format: | Article |
Language: | English |
Published: |
MDPI AG
2020-09-01
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Series: | Antibodies |
Subjects: | |
Online Access: | https://www.mdpi.com/2073-4468/9/3/45 |