Disregulating processes in the blood system during cancer

Hematologic disturbances in patients with solid malignant tumors, their development mechanism, value, modern pathogenetic principles of correction are considered in the article. The role of cytokines, erythropoietin, blood loss, metastasing of tumors, depressing bone marrow hemopoiesis and increased...

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Main Authors: V. S. Lavrova, Ye. N. Chernova, G. V. Karpova, Ye. A. Stepovaya, Yu. A. Kozlov, T. A. Loukiyanova
Format: Article
Language:English
Published: Siberian State Medical University (Tomsk) 2006-06-01
Series:Бюллетень сибирской медицины
Subjects:
Online Access:https://bulletin.ssmu.ru/jour/article/view/3068
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author V. S. Lavrova
Ye. N. Chernova
G. V. Karpova
Ye. A. Stepovaya
Yu. A. Kozlov
T. A. Loukiyanova
author_facet V. S. Lavrova
Ye. N. Chernova
G. V. Karpova
Ye. A. Stepovaya
Yu. A. Kozlov
T. A. Loukiyanova
author_sort V. S. Lavrova
collection DOAJ
description Hematologic disturbances in patients with solid malignant tumors, their development mechanism, value, modern pathogenetic principles of correction are considered in the article. The role of cytokines, erythropoietin, blood loss, metastasing of tumors, depressing bone marrow hemopoiesis and increased destroying erythrocytes, microcirculatory disturbances, iron exchange and vitamin B12 in pathogenesis of cancer anemia and also disregulating processes in myeloid hemopoiesis which manifest in the development of neutrophil leucocytosis , eosinophylia and leukemoid reactions in patients having malignant neoplasms is described in details. Hematologic disturbances in malignant growth are frequent manifestations of paraneoplastic syndrome which is a result of system influence of the tumor on the organism. Radial and chemotherapy increase disregulating processes in this vitally important system which require improved methods of their correction.
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spelling doaj.art-427737a515d74eb5bf6d040a22447b7b2023-03-13T09:58:05ZengSiberian State Medical University (Tomsk)Бюллетень сибирской медицины1682-03631819-36842006-06-0152758310.20538/1682-0363-2006-2-75-831726Disregulating processes in the blood system during cancerV. S. Lavrova0Ye. N. Chernova1G. V. Karpova2Ye. A. Stepovaya3Yu. A. Kozlov4T. A. Loukiyanova5Сибирский государственный медицинский университетСибирский государственный медицинский университетСибирский государственный медицинский университетСибирский государственный медицинский университетСибирский государственный медицинский университетСибирский государственный медицинский университетHematologic disturbances in patients with solid malignant tumors, their development mechanism, value, modern pathogenetic principles of correction are considered in the article. The role of cytokines, erythropoietin, blood loss, metastasing of tumors, depressing bone marrow hemopoiesis and increased destroying erythrocytes, microcirculatory disturbances, iron exchange and vitamin B12 in pathogenesis of cancer anemia and also disregulating processes in myeloid hemopoiesis which manifest in the development of neutrophil leucocytosis , eosinophylia and leukemoid reactions in patients having malignant neoplasms is described in details. Hematologic disturbances in malignant growth are frequent manifestations of paraneoplastic syndrome which is a result of system influence of the tumor on the organism. Radial and chemotherapy increase disregulating processes in this vitally important system which require improved methods of their correction.https://bulletin.ssmu.ru/jour/article/view/3068гематологические нарушениязлокачественные опухолипаранеопластический синдромраковая анемияhematologic disturbancesmalignant tumorsparaneoplastic syndromecancer anemia
spellingShingle V. S. Lavrova
Ye. N. Chernova
G. V. Karpova
Ye. A. Stepovaya
Yu. A. Kozlov
T. A. Loukiyanova
Disregulating processes in the blood system during cancer
Бюллетень сибирской медицины
гематологические нарушения
злокачественные опухоли
паранеопластический синдром
раковая анемия
hematologic disturbances
malignant tumors
paraneoplastic syndrome
cancer anemia
title Disregulating processes in the blood system during cancer
title_full Disregulating processes in the blood system during cancer
title_fullStr Disregulating processes in the blood system during cancer
title_full_unstemmed Disregulating processes in the blood system during cancer
title_short Disregulating processes in the blood system during cancer
title_sort disregulating processes in the blood system during cancer
topic гематологические нарушения
злокачественные опухоли
паранеопластический синдром
раковая анемия
hematologic disturbances
malignant tumors
paraneoplastic syndrome
cancer anemia
url https://bulletin.ssmu.ru/jour/article/view/3068
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AT yenchernova disregulatingprocessesinthebloodsystemduringcancer
AT gvkarpova disregulatingprocessesinthebloodsystemduringcancer
AT yeastepovaya disregulatingprocessesinthebloodsystemduringcancer
AT yuakozlov disregulatingprocessesinthebloodsystemduringcancer
AT taloukiyanova disregulatingprocessesinthebloodsystemduringcancer