Cardioprotective Effect of Reamberin in Ischemic — Reperfusion Injury
Objective: to identify the effectiveness of the drug Reamberin in complex intensive threatment of patients with cardiac surgery in heart fibrillation and remodeling of prosthetic heart valves and plastic defects of atrial and ventricular septa. Reamberin according the following protocol: 400 ml in t...
| Main Authors: | , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Federal Research and Clinical Center of Intensive Care Medicine and Rehabilitology, Moscow, Russia
2016-10-01
|
| Series: | Общая реаниматология |
| Subjects: | |
| Online Access: | https://www.reanimatology.com/rmt/article/view/1539 |
| _version_ | 1797874191128592384 |
|---|---|
| author | L. V. Nowicka-Usenko A. V. Tsarev |
| author_facet | L. V. Nowicka-Usenko A. V. Tsarev |
| author_sort | L. V. Nowicka-Usenko |
| collection | DOAJ |
| description | Objective: to identify the effectiveness of the drug Reamberin in complex intensive threatment of patients with cardiac surgery in heart fibrillation and remodeling of prosthetic heart valves and plastic defects of atrial and ventricular septa. Reamberin according the following protocol: 400 ml in the first 6 hours of the postoperative period as an intravenous drip at a rate of 60—90 drops/min. In group 2 (control group), 26 patients received standard intensive care medication. In addition to standard clinical and laboratory tests during the study following components were quantitavile determined in blood: troponin I, lactate dehydrogenase, creatine kinase, isofractions of creatine kinaseMB, transaminases (alanine aminotransferase and aspartate aminotransferase).Results. Treatment of patients from the main group revealed the recovery of functional parametersof the myocardium, improved dynamics of cardiac enzymes and normalization of blood acid-base status.Conclusion. Inclusion in the complex intensive therapy of post#cardiac surgery of the Reamberin in patients experiencing heart fibrillation after the cardiopulmonary bypass followed by electrical defibrillation improved the clinical course of the early postoperative period and reduced the risk of complications and early mortality. |
| first_indexed | 2024-04-10T01:28:05Z |
| format | Article |
| id | doaj.art-427a4a329b1b4b3ab56620695f93b97d |
| institution | Directory Open Access Journal |
| issn | 1813-9779 2411-7110 |
| language | English |
| last_indexed | 2024-04-10T01:28:05Z |
| publishDate | 2016-10-01 |
| publisher | Federal Research and Clinical Center of Intensive Care Medicine and Rehabilitology, Moscow, Russia |
| record_format | Article |
| series | Общая реаниматология |
| spelling | doaj.art-427a4a329b1b4b3ab56620695f93b97d2023-03-13T09:32:54ZengFederal Research and Clinical Center of Intensive Care Medicine and Rehabilitology, Moscow, RussiaОбщая реаниматология1813-97792411-71102016-10-01124495610.15360/1813-9779-2016-4-49-561516Cardioprotective Effect of Reamberin in Ischemic — Reperfusion InjuryL. V. Nowicka-Usenko0A. V. Tsarev1Днепропетровская медицинская академия Минздрава УкраиныДнепропетровская медицинская академия Минздрава УкраиныObjective: to identify the effectiveness of the drug Reamberin in complex intensive threatment of patients with cardiac surgery in heart fibrillation and remodeling of prosthetic heart valves and plastic defects of atrial and ventricular septa. Reamberin according the following protocol: 400 ml in the first 6 hours of the postoperative period as an intravenous drip at a rate of 60—90 drops/min. In group 2 (control group), 26 patients received standard intensive care medication. In addition to standard clinical and laboratory tests during the study following components were quantitavile determined in blood: troponin I, lactate dehydrogenase, creatine kinase, isofractions of creatine kinaseMB, transaminases (alanine aminotransferase and aspartate aminotransferase).Results. Treatment of patients from the main group revealed the recovery of functional parametersof the myocardium, improved dynamics of cardiac enzymes and normalization of blood acid-base status.Conclusion. Inclusion in the complex intensive therapy of post#cardiac surgery of the Reamberin in patients experiencing heart fibrillation after the cardiopulmonary bypass followed by electrical defibrillation improved the clinical course of the early postoperative period and reduced the risk of complications and early mortality.https://www.reanimatology.com/rmt/article/view/1539реамберинкардиохирургияишемическиреперфузионное повреждение миокардаинтенсивная терапия |
| spellingShingle | L. V. Nowicka-Usenko A. V. Tsarev Cardioprotective Effect of Reamberin in Ischemic — Reperfusion Injury Общая реаниматология реамберин кардиохирургия ишемическиреперфузионное повреждение миокарда интенсивная терапия |
| title | Cardioprotective Effect of Reamberin in Ischemic — Reperfusion Injury |
| title_full | Cardioprotective Effect of Reamberin in Ischemic — Reperfusion Injury |
| title_fullStr | Cardioprotective Effect of Reamberin in Ischemic — Reperfusion Injury |
| title_full_unstemmed | Cardioprotective Effect of Reamberin in Ischemic — Reperfusion Injury |
| title_short | Cardioprotective Effect of Reamberin in Ischemic — Reperfusion Injury |
| title_sort | cardioprotective effect of reamberin in ischemic reperfusion injury |
| topic | реамберин кардиохирургия ишемическиреперфузионное повреждение миокарда интенсивная терапия |
| url | https://www.reanimatology.com/rmt/article/view/1539 |
| work_keys_str_mv | AT lvnowickausenko cardioprotectiveeffectofreamberininischemicreperfusioninjury AT avtsarev cardioprotectiveeffectofreamberininischemicreperfusioninjury |