2-{[5-(Diphenylmethyl)-1,3,4-oxadiazol-2-yl]sulfanyl}-N-(pyrazin-2-yl)acetamide
S-Alkylation of 5-(diphenylmethyl)-1,3,4-oxadiazole-2(3H)-thione (3) by 2-chloro-N-(pyrazin-2-yl)acetamide (2) affords the title compound, 2-{[5-(diphenylmethyl)-1,3,4-oxadiazol-2-yl]sulfanyl}-N-(pyrazin-2-yl)acetamide (4). The intermediate (2), in turn, was prepared by the acetylation of 2-aminopyr...
| Main Authors: | , , , |
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| Format: | Article |
| Language: | English |
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MDPI AG
2013-05-01
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| Series: | Molbank |
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| Online Access: | http://www.mdpi.com/1422-8599/2013/2/M800 |
| _version_ | 1819020452515807232 |
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| author | Balladka Kunhanna Sarojini Seranthimata Samshuddin Badiadka Narayana Prakash S. Nayak |
| author_facet | Balladka Kunhanna Sarojini Seranthimata Samshuddin Badiadka Narayana Prakash S. Nayak |
| author_sort | Balladka Kunhanna Sarojini |
| collection | DOAJ |
| description | S-Alkylation of 5-(diphenylmethyl)-1,3,4-oxadiazole-2(3H)-thione (3) by 2-chloro-N-(pyrazin-2-yl)acetamide (2) affords the title compound, 2-{[5-(diphenylmethyl)-1,3,4-oxadiazol-2-yl]sulfanyl}-N-(pyrazin-2-yl)acetamide (4). The intermediate (2), in turn, was prepared by the acetylation of 2-aminopyrazine (1) with chloroacetyl chloride. The structure of the newly synthesized compound is characterized by IR, NMR and mass spectral data. |
| first_indexed | 2024-12-21T03:51:26Z |
| format | Article |
| id | doaj.art-427bf81b6b1f430ba8d90cfd4c2d8e51 |
| institution | Directory Open Access Journal |
| issn | 1422-8599 |
| language | English |
| last_indexed | 2024-12-21T03:51:26Z |
| publishDate | 2013-05-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Molbank |
| spelling | doaj.art-427bf81b6b1f430ba8d90cfd4c2d8e512022-12-21T19:16:58ZengMDPI AGMolbank1422-85992013-05-0120132M80010.3390/M8002-{[5-(Diphenylmethyl)-1,3,4-oxadiazol-2-yl]sulfanyl}-N-(pyrazin-2-yl)acetamideBalladka Kunhanna SarojiniSeranthimata SamshuddinBadiadka NarayanaPrakash S. NayakS-Alkylation of 5-(diphenylmethyl)-1,3,4-oxadiazole-2(3H)-thione (3) by 2-chloro-N-(pyrazin-2-yl)acetamide (2) affords the title compound, 2-{[5-(diphenylmethyl)-1,3,4-oxadiazol-2-yl]sulfanyl}-N-(pyrazin-2-yl)acetamide (4). The intermediate (2), in turn, was prepared by the acetylation of 2-aminopyrazine (1) with chloroacetyl chloride. The structure of the newly synthesized compound is characterized by IR, NMR and mass spectral data.http://www.mdpi.com/1422-8599/2013/2/M8001,3,4-oxadiazolepyrazineS-alkylationthioether |
| spellingShingle | Balladka Kunhanna Sarojini Seranthimata Samshuddin Badiadka Narayana Prakash S. Nayak 2-{[5-(Diphenylmethyl)-1,3,4-oxadiazol-2-yl]sulfanyl}-N-(pyrazin-2-yl)acetamide Molbank 1,3,4-oxadiazole pyrazine S-alkylation thioether |
| title | 2-{[5-(Diphenylmethyl)-1,3,4-oxadiazol-2-yl]sulfanyl}-N-(pyrazin-2-yl)acetamide |
| title_full | 2-{[5-(Diphenylmethyl)-1,3,4-oxadiazol-2-yl]sulfanyl}-N-(pyrazin-2-yl)acetamide |
| title_fullStr | 2-{[5-(Diphenylmethyl)-1,3,4-oxadiazol-2-yl]sulfanyl}-N-(pyrazin-2-yl)acetamide |
| title_full_unstemmed | 2-{[5-(Diphenylmethyl)-1,3,4-oxadiazol-2-yl]sulfanyl}-N-(pyrazin-2-yl)acetamide |
| title_short | 2-{[5-(Diphenylmethyl)-1,3,4-oxadiazol-2-yl]sulfanyl}-N-(pyrazin-2-yl)acetamide |
| title_sort | 2 5 diphenylmethyl 1 3 4 oxadiazol 2 yl sulfanyl n pyrazin 2 yl acetamide |
| topic | 1,3,4-oxadiazole pyrazine S-alkylation thioether |
| url | http://www.mdpi.com/1422-8599/2013/2/M800 |
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