Preparation of Azoxystrobin-Zinc Metal–Organic Framework/Biomass Charcoal Composite Materials and Application in the Prevention and Control of Gray Mold in Tomato
In order to reduce the use of fungicide and ensure food safety, it is necessary to develop fungicide with low toxicity and high efficiency to reduce residues. Azoxystrobin (AZOX), which is derived from mushrooms, is an excellent choice. However, conventional AZOX release is difficult to regulate. In...
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| Format: | Article |
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MDPI AG
2023-10-01
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| Series: | International Journal of Molecular Sciences |
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| Online Access: | https://www.mdpi.com/1422-0067/24/21/15609 |
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| author | Xiao Han Yinjie Qian Jiapeng Li Zhongkai Zhang Jinbo Guo Ning Zhang Longyu Liu Zhiqiang Cheng Xiaobin Yu |
| author_facet | Xiao Han Yinjie Qian Jiapeng Li Zhongkai Zhang Jinbo Guo Ning Zhang Longyu Liu Zhiqiang Cheng Xiaobin Yu |
| author_sort | Xiao Han |
| collection | DOAJ |
| description | In order to reduce the use of fungicide and ensure food safety, it is necessary to develop fungicide with low toxicity and high efficiency to reduce residues. Azoxystrobin (AZOX), which is derived from mushrooms, is an excellent choice. However, conventional AZOX release is difficult to regulate. In this paper, a pH-responsive fungicide delivery system for the preparation of AZOX by impregnation method was reported. The Zinc metal–organic framework/Biomass charcoal (ZIF-8/BC) support was first prepared, and subsequently, the AZOX-ZIF-8/BC nano fungicide was prepared by adsorption of AZOX onto ZIF-8/BC by dipping. Gray mold, caused by <i>Botrytis cinerea</i>, is one of the most important crop diseases worldwide. AZOX-ZIF-8/BC could respond to oxalic acid produced by <i>Botrytis cinerea</i> to release loaded AZOX. When pH = 4.8, it was 48.42% faster than when pH = 8.2. The loading of AZOX on ZIF-8/BC was 19.83%. In vitro and pot experiments showed that AZOX-ZIF-8/BC had significant fungicidal activity, and 300 mg/L concentration of AZOX-ZIF-8-BC could be considered as a safe and effective control of <i>Botrytis cinerea</i>. The above results indicated that the prepared AZOX-ZIF-8/BC not only exhibited good drug efficacy but also demonstrated pH-responsive fungicide release. |
| first_indexed | 2024-03-11T11:28:35Z |
| format | Article |
| id | doaj.art-427d6f1e5e0d46f0abc2a2eb7a16c959 |
| institution | Directory Open Access Journal |
| issn | 1661-6596 1422-0067 |
| language | English |
| last_indexed | 2024-03-11T11:28:35Z |
| publishDate | 2023-10-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | International Journal of Molecular Sciences |
| spelling | doaj.art-427d6f1e5e0d46f0abc2a2eb7a16c9592023-11-10T15:04:36ZengMDPI AGInternational Journal of Molecular Sciences1661-65961422-00672023-10-0124211560910.3390/ijms242115609Preparation of Azoxystrobin-Zinc Metal–Organic Framework/Biomass Charcoal Composite Materials and Application in the Prevention and Control of Gray Mold in TomatoXiao Han0Yinjie Qian1Jiapeng Li2Zhongkai Zhang3Jinbo Guo4Ning Zhang5Longyu Liu6Zhiqiang Cheng7Xiaobin Yu8College of Plant Protection, Jilin Agricultural University, Changchun 130118, ChinaCollege of Plant Protection, Jilin Agricultural University, Changchun 130118, ChinaCollege of Resources and Environment, Jilin Agricultural University, Changchun 130118, ChinaCollege of Plant Protection, Jilin Agricultural University, Changchun 130118, ChinaCollege of Plant Protection, Jilin Agricultural University, Changchun 130118, ChinaCollege of Plant Protection, Jilin Agricultural University, Changchun 130118, ChinaCollege of Plant Protection, Jilin Agricultural University, Changchun 130118, ChinaCollege of Resources and Environment, Jilin Agricultural University, Changchun 130118, ChinaCollege of Plant Protection, Jilin Agricultural University, Changchun 130118, ChinaIn order to reduce the use of fungicide and ensure food safety, it is necessary to develop fungicide with low toxicity and high efficiency to reduce residues. Azoxystrobin (AZOX), which is derived from mushrooms, is an excellent choice. However, conventional AZOX release is difficult to regulate. In this paper, a pH-responsive fungicide delivery system for the preparation of AZOX by impregnation method was reported. The Zinc metal–organic framework/Biomass charcoal (ZIF-8/BC) support was first prepared, and subsequently, the AZOX-ZIF-8/BC nano fungicide was prepared by adsorption of AZOX onto ZIF-8/BC by dipping. Gray mold, caused by <i>Botrytis cinerea</i>, is one of the most important crop diseases worldwide. AZOX-ZIF-8/BC could respond to oxalic acid produced by <i>Botrytis cinerea</i> to release loaded AZOX. When pH = 4.8, it was 48.42% faster than when pH = 8.2. The loading of AZOX on ZIF-8/BC was 19.83%. In vitro and pot experiments showed that AZOX-ZIF-8/BC had significant fungicidal activity, and 300 mg/L concentration of AZOX-ZIF-8-BC could be considered as a safe and effective control of <i>Botrytis cinerea</i>. The above results indicated that the prepared AZOX-ZIF-8/BC not only exhibited good drug efficacy but also demonstrated pH-responsive fungicide release.https://www.mdpi.com/1422-0067/24/21/15609AZOX-ZIF-8/BC<i>Botrytis cinerea</i>fungicidenano fungicidepH-responsive release |
| spellingShingle | Xiao Han Yinjie Qian Jiapeng Li Zhongkai Zhang Jinbo Guo Ning Zhang Longyu Liu Zhiqiang Cheng Xiaobin Yu Preparation of Azoxystrobin-Zinc Metal–Organic Framework/Biomass Charcoal Composite Materials and Application in the Prevention and Control of Gray Mold in Tomato International Journal of Molecular Sciences AZOX-ZIF-8/BC <i>Botrytis cinerea</i> fungicide nano fungicide pH-responsive release |
| title | Preparation of Azoxystrobin-Zinc Metal–Organic Framework/Biomass Charcoal Composite Materials and Application in the Prevention and Control of Gray Mold in Tomato |
| title_full | Preparation of Azoxystrobin-Zinc Metal–Organic Framework/Biomass Charcoal Composite Materials and Application in the Prevention and Control of Gray Mold in Tomato |
| title_fullStr | Preparation of Azoxystrobin-Zinc Metal–Organic Framework/Biomass Charcoal Composite Materials and Application in the Prevention and Control of Gray Mold in Tomato |
| title_full_unstemmed | Preparation of Azoxystrobin-Zinc Metal–Organic Framework/Biomass Charcoal Composite Materials and Application in the Prevention and Control of Gray Mold in Tomato |
| title_short | Preparation of Azoxystrobin-Zinc Metal–Organic Framework/Biomass Charcoal Composite Materials and Application in the Prevention and Control of Gray Mold in Tomato |
| title_sort | preparation of azoxystrobin zinc metal organic framework biomass charcoal composite materials and application in the prevention and control of gray mold in tomato |
| topic | AZOX-ZIF-8/BC <i>Botrytis cinerea</i> fungicide nano fungicide pH-responsive release |
| url | https://www.mdpi.com/1422-0067/24/21/15609 |
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