Antiproliferative and apoptotic activities of tomato bioactive metabolite on MDA-MB-435 cell line: in silico molecular modeling and molecular dynamics investigation

Antiproliferative and apoptotic activities of tomato bioactive metabolite on MDA-MB-435 cell line: in silico molecular modeling and molecular dynamics investigation

Abstract Background As an external organ, the skin protects the whole body against hazardous external influences. Ultraviolet (UV) radiation is one of these influences which in high amount can cause DNA damage, and even skin cancer. Hence, it is important to promote skin protection with commercially...

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Bibliographic Details
Main Authors: Yasmin A. Elkhawas, Menna A. Ewida, Heba A. Ewida, Mariam Gonaid, Noha Khalil
Format: Article
Language:English
Published: SpringerOpen 2023-10-01
Series:Future Journal of Pharmaceutical Sciences
Subjects:
Cell cycle
MDA-MB-435
Melanoma
Molecular docking
Molecular dynamic
ADME
Online Access:https://doi.org/10.1186/s43094-023-00538-5

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