Morbillivirus glycoprotein expression induces ER stress, alters Ca2+ homeostasis and results in the release of vasostatin.

Morbillivirus glycoprotein expression induces ER stress, alters Ca2+ homeostasis and results in the release of vasostatin.

Although the pathology of Morbillivirus in the central nervous system (CNS) is well described, the molecular basis of neurodegenerative events still remains poorly understood. As a model to explore Morbillivirus-mediated CNS dysfunctions, we used canine distemper virus (CDV) that we inoculated into...

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Main Authors: Jean-Marc Brunner, Philippe Plattet, Marie-Agnès Doucey, Lia Rosso, Thomas Curie, Alexandra Montagner, Riccardo Wittek, Marc Vandelvelde, Andreas Zurbriggen, Harald Hirling, Béatrice Desvergne
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3293893?pdf=render

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