Percutaneous device closure of patent ductus arteriosus in adult patients with 10-year follow-up
Objectives: We report our 10-year experience with transcatheter closure of patent ductus arteriosus (PDA) in adult using different closure devices. Background: Transcatheter closure of PDA in adults can be challenging because of frequently associated comorbidities. Reports on immediate and intermedi...
| Main Authors: | , , , , , , , , , |
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| Format: | Article |
| Language: | English |
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Wolters Kluwer Medknow Publications
2019-01-01
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| Series: | Heart Views |
| Subjects: | |
| Online Access: | http://www.heartviews.org/article.asp?issn=1995-705X;year=2019;volume=20;issue=4;spage=139;epage=145;aulast=Alkashkari |
| _version_ | 1818178864561520640 |
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| author | Wail Alkashkari Saad Albugami Jamilah Alrahimi Mohammed Althobaiti Abdulhalim Kinsara Ahmed Abousa Ahmed Krimly Atif Alzahrani Akram Niazi Hayam Aburemish |
| author_facet | Wail Alkashkari Saad Albugami Jamilah Alrahimi Mohammed Althobaiti Abdulhalim Kinsara Ahmed Abousa Ahmed Krimly Atif Alzahrani Akram Niazi Hayam Aburemish |
| author_sort | Wail Alkashkari |
| collection | DOAJ |
| description | Objectives: We report our 10-year experience with transcatheter closure of patent ductus arteriosus (PDA) in adult using different closure devices.
Background: Transcatheter closure of PDA in adults can be challenging because of frequently associated comorbidities. Reports on immediate and intermediate-term results of PDA closure are excellent. This study aimed to provide the outcomes of PDA closure using different devices on long and very long term follow-up in adults.
Materials and Methods: Between September 2009 and December 2018, data were retrospectively reviewed from 27 patients who underwent transcatheter closure of PDA. Outcome parameters were procedural success, procedure-related complications, evidence of residual shunt, and improvement in the signs/symptoms for which the procedure was performed. The mean follow-up interval was 72 months.
Results: A device was successfully implanted in 27 of 27 patients (15 females). Median age and weight were 24 years (range: 18–57 years) and 69 kg (range: 53–102 kg), respectively. The mean PDA diameter was 4.1 ± 2.1 mm. Devices used were Amplatzer Duct Occluder (19/27), Occlutech Duct Occluder (6/27), and PFM Nit-Occlud (2/27). Doppler transthoracic echocardiography (TTE) demonstrated 92.6% of full occlusion at day 1, rising to 96.3% at 1 month. Three procedure-related complications occurred with no death. Among symptomatic 26 patients (96.3%), there was marked improvement in symptoms. Among 22 patients (81.5%) for whom the procedure was performed to address left ventricular (LV) enlargement, there was reduction or stabilization in LV size on serial TTEs.
Conclusions: Transcatheter closure of PDA in the adult patient appears to be safe and effective. |
| first_indexed | 2024-12-11T20:54:45Z |
| format | Article |
| id | doaj.art-42848b0dc7f34714b81251d4aaf38afa |
| institution | Directory Open Access Journal |
| issn | 1995-705X |
| language | English |
| last_indexed | 2024-12-11T20:54:45Z |
| publishDate | 2019-01-01 |
| publisher | Wolters Kluwer Medknow Publications |
| record_format | Article |
| series | Heart Views |
| spelling | doaj.art-42848b0dc7f34714b81251d4aaf38afa2022-12-22T00:51:09ZengWolters Kluwer Medknow PublicationsHeart Views1995-705X2019-01-0120413914510.4103/HEARTVIEWS.HEARTVIEWS_21_19Percutaneous device closure of patent ductus arteriosus in adult patients with 10-year follow-upWail AlkashkariSaad AlbugamiJamilah AlrahimiMohammed AlthobaitiAbdulhalim KinsaraAhmed AbousaAhmed KrimlyAtif AlzahraniAkram NiaziHayam AburemishObjectives: We report our 10-year experience with transcatheter closure of patent ductus arteriosus (PDA) in adult using different closure devices. Background: Transcatheter closure of PDA in adults can be challenging because of frequently associated comorbidities. Reports on immediate and intermediate-term results of PDA closure are excellent. This study aimed to provide the outcomes of PDA closure using different devices on long and very long term follow-up in adults. Materials and Methods: Between September 2009 and December 2018, data were retrospectively reviewed from 27 patients who underwent transcatheter closure of PDA. Outcome parameters were procedural success, procedure-related complications, evidence of residual shunt, and improvement in the signs/symptoms for which the procedure was performed. The mean follow-up interval was 72 months. Results: A device was successfully implanted in 27 of 27 patients (15 females). Median age and weight were 24 years (range: 18–57 years) and 69 kg (range: 53–102 kg), respectively. The mean PDA diameter was 4.1 ± 2.1 mm. Devices used were Amplatzer Duct Occluder (19/27), Occlutech Duct Occluder (6/27), and PFM Nit-Occlud (2/27). Doppler transthoracic echocardiography (TTE) demonstrated 92.6% of full occlusion at day 1, rising to 96.3% at 1 month. Three procedure-related complications occurred with no death. Among symptomatic 26 patients (96.3%), there was marked improvement in symptoms. Among 22 patients (81.5%) for whom the procedure was performed to address left ventricular (LV) enlargement, there was reduction or stabilization in LV size on serial TTEs. Conclusions: Transcatheter closure of PDA in the adult patient appears to be safe and effective.http://www.heartviews.org/article.asp?issn=1995-705X;year=2019;volume=20;issue=4;spage=139;epage=145;aulast=Alkashkaricardiac catheterizationheart failurepatent ductus arteriosuspulmonary hypertension |
| spellingShingle | Wail Alkashkari Saad Albugami Jamilah Alrahimi Mohammed Althobaiti Abdulhalim Kinsara Ahmed Abousa Ahmed Krimly Atif Alzahrani Akram Niazi Hayam Aburemish Percutaneous device closure of patent ductus arteriosus in adult patients with 10-year follow-up Heart Views cardiac catheterization heart failure patent ductus arteriosus pulmonary hypertension |
| title | Percutaneous device closure of patent ductus arteriosus in adult patients with 10-year follow-up |
| title_full | Percutaneous device closure of patent ductus arteriosus in adult patients with 10-year follow-up |
| title_fullStr | Percutaneous device closure of patent ductus arteriosus in adult patients with 10-year follow-up |
| title_full_unstemmed | Percutaneous device closure of patent ductus arteriosus in adult patients with 10-year follow-up |
| title_short | Percutaneous device closure of patent ductus arteriosus in adult patients with 10-year follow-up |
| title_sort | percutaneous device closure of patent ductus arteriosus in adult patients with 10 year follow up |
| topic | cardiac catheterization heart failure patent ductus arteriosus pulmonary hypertension |
| url | http://www.heartviews.org/article.asp?issn=1995-705X;year=2019;volume=20;issue=4;spage=139;epage=145;aulast=Alkashkari |
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