Human Immunodeficiency Virus (HIV) infection with Multiple Comorbidities in COVID-19 Pandemic Era: A Case Report

Coronavirus disease-19 (COVID-19) and Human Immunodeficiency Virus (HIV) were pandemic diseases that affected the healthcare system worldwide. Decline immune system in HIV and accompanying opportunistic infection may worsen the outcome and prognosis of COVID-19 infection. Comprehensive diagnosis and...

Full description

Bibliographic Details
Main Author: Dwitya Elvira
Format: Article
Language:Indonesian
Published: Universitas Pembangunan Nasional Veteran Jakarta 2021-11-01
Series:Jurnal Profesi Medika
Subjects:
Online Access:https://ejournal.upnvj.ac.id/index.php/JPM/article/view/3042
_version_ 1811218882400092160
author Dwitya Elvira
author_facet Dwitya Elvira
author_sort Dwitya Elvira
collection DOAJ
description Coronavirus disease-19 (COVID-19) and Human Immunodeficiency Virus (HIV) were pandemic diseases that affected the healthcare system worldwide. Decline immune system in HIV and accompanying opportunistic infection may worsen the outcome and prognosis of COVID-19 infection. Comprehensive diagnosis and treatment were crucial with HIV patients with a very low immune response. This is our first case report of 50 years old man recently known with HIV and confirmed COVID-19 from PCR swab at once. We found several comorbidities through a comprehensive examination of clinical and laboratory, such as bicytopenia (anemia and thrombocytopenia), acute renal failure, increased liver transaminase, and coagulation disorder (increased PT/APTT) D-dimer), hypoalbuminemia and extremely low CD4. Oral candidiasis, chronic B hepatitis, and lung tuberculosis also present as opportunistic infections in this patient. One dose of antiviral oseltamivir was given each day interval (considering the patient's renal function) accompanied with immediate resuscitation, multivitamins, fluconazole, and cotrimoxazole given. After resolving an acute condition, oral tuberculosis treatment was given, continued with antiretroviral therapy, and advised the patient to routine control in the outpatient department. Future research should address the significance of CD4 lymphocyte count or viral load to measure patients with HIV's immune system and clinical status, risk of opportunistic infection, and prognostic in this pandemic COVID-19 era.
first_indexed 2024-04-12T07:16:53Z
format Article
id doaj.art-428929cc1e9c421081ad4b4699241448
institution Directory Open Access Journal
issn 0216-3438
2621-1122
language Indonesian
last_indexed 2024-04-12T07:16:53Z
publishDate 2021-11-01
publisher Universitas Pembangunan Nasional Veteran Jakarta
record_format Article
series Jurnal Profesi Medika
spelling doaj.art-428929cc1e9c421081ad4b46992414482022-12-22T03:42:25ZindUniversitas Pembangunan Nasional Veteran JakartaJurnal Profesi Medika0216-34382621-11222021-11-0115010.33533/jpm.v15i0.30421182Human Immunodeficiency Virus (HIV) infection with Multiple Comorbidities in COVID-19 Pandemic Era: A Case ReportDwitya Elvira0Allergy and Clinical Immunology Subdivision, Department of Internal Medicine, Faculty of Medicine, Universitas Andalas / M. Djamil Hospital, Padang, West Sumatera, Indonesia AndalasCoronavirus disease-19 (COVID-19) and Human Immunodeficiency Virus (HIV) were pandemic diseases that affected the healthcare system worldwide. Decline immune system in HIV and accompanying opportunistic infection may worsen the outcome and prognosis of COVID-19 infection. Comprehensive diagnosis and treatment were crucial with HIV patients with a very low immune response. This is our first case report of 50 years old man recently known with HIV and confirmed COVID-19 from PCR swab at once. We found several comorbidities through a comprehensive examination of clinical and laboratory, such as bicytopenia (anemia and thrombocytopenia), acute renal failure, increased liver transaminase, and coagulation disorder (increased PT/APTT) D-dimer), hypoalbuminemia and extremely low CD4. Oral candidiasis, chronic B hepatitis, and lung tuberculosis also present as opportunistic infections in this patient. One dose of antiviral oseltamivir was given each day interval (considering the patient's renal function) accompanied with immediate resuscitation, multivitamins, fluconazole, and cotrimoxazole given. After resolving an acute condition, oral tuberculosis treatment was given, continued with antiretroviral therapy, and advised the patient to routine control in the outpatient department. Future research should address the significance of CD4 lymphocyte count or viral load to measure patients with HIV's immune system and clinical status, risk of opportunistic infection, and prognostic in this pandemic COVID-19 era.https://ejournal.upnvj.ac.id/index.php/JPM/article/view/3042covid-19hiv/aidsco-infectionmultiple comorbidities
spellingShingle Dwitya Elvira
Human Immunodeficiency Virus (HIV) infection with Multiple Comorbidities in COVID-19 Pandemic Era: A Case Report
Jurnal Profesi Medika
covid-19
hiv/aids
co-infection
multiple comorbidities
title Human Immunodeficiency Virus (HIV) infection with Multiple Comorbidities in COVID-19 Pandemic Era: A Case Report
title_full Human Immunodeficiency Virus (HIV) infection with Multiple Comorbidities in COVID-19 Pandemic Era: A Case Report
title_fullStr Human Immunodeficiency Virus (HIV) infection with Multiple Comorbidities in COVID-19 Pandemic Era: A Case Report
title_full_unstemmed Human Immunodeficiency Virus (HIV) infection with Multiple Comorbidities in COVID-19 Pandemic Era: A Case Report
title_short Human Immunodeficiency Virus (HIV) infection with Multiple Comorbidities in COVID-19 Pandemic Era: A Case Report
title_sort human immunodeficiency virus hiv infection with multiple comorbidities in covid 19 pandemic era a case report
topic covid-19
hiv/aids
co-infection
multiple comorbidities
url https://ejournal.upnvj.ac.id/index.php/JPM/article/view/3042
work_keys_str_mv AT dwityaelvira humanimmunodeficiencyvirushivinfectionwithmultiplecomorbiditiesincovid19pandemiceraacasereport