| Summary: | Introduction
This study aims to evaluate the prevalence of xerostomia in a healthy
population with e-cigarettes and/or combustible tobacco.
Methods
The following electronic databases were searched: Web of Science,
Chinese Biomedical Literature Database (CBM), PubMed, Cochrane Library,
Embase, Chinese National Knowledge Infrastructure (CNKI), China Science and
Technology Journal Database (VIP), and Wan-Fang Database, from 1 January
2000 to 20 October 2022. The language was limited to Chinese and English. The
data were analyzed using Stata 15.0, and the prevalence of xerostomia in different
smokers is reported.
Results
A total of 14 studies were included, with a total sample size of 6827
cases. The overall prevalence of xerostomia was 26% (95% CI: 18–35). In the
combustible tobacco population, the prevalence of xerostomia was 24% (95% CI:
21–27), while among e-cigarette users it was 33% (95% CI: 18–48).
Conclusions
Current evidence suggests that the prevalence of xerostomia is high
in healthy smoking populations. These findings are restricted by the number
and quality of the included studies and need to be validated by additional highquality
studies.
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