Sex-related differences in the response of anti-platelet drug therapies targeting purinergic signaling pathways in sepsis

Sepsis, a complex clinical syndrome resulting from a serious infection, is a major healthcare problem associated with high mortality. Sex-related differences in the immune response to sepsis have been proposed but the mechanism is still unknown. Purinergic signaling is a sex-specific regulatory mech...

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Bibliographic Details
Main Authors: Emmanuel Boadi Amoafo, Philomena Entsie, Samara Albayati, Glenn P. Dorsam, Satya P. Kunapuli, Laurie E. Kilpatrick, Elisabetta Liverani
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-11-01
Series:Frontiers in Immunology
Subjects:
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2022.1015577/full