Activation of the Mitochondrial Unfolded Protein Response: A New Therapeutic Target?

Activation of the Mitochondrial Unfolded Protein Response: A New Therapeutic Target?

Mitochondrial dysfunction is a key hub that is common to many diseases. Mitochondria’s role in energy production, calcium homeostasis, and ROS balance makes them essential for cell survival and fitness. However, there are no effective treatments for most mitochondrial and related diseases to this da...

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Bibliographic Details
Main Authors: Juan M. Suárez-Rivero, Carmen J. Pastor-Maldonado, Suleva Povea-Cabello, Mónica Álvarez-Córdoba, Irene Villalón-García, Marta Talaverón-Rey, Alejandra Suárez-Carrillo, Manuel Munuera-Cabeza, Diana Reche-López, Paula Cilleros-Holgado, Rocío Piñero-Pérez, José A. Sánchez-Alcázar
Format: Article
Language:English
Published: MDPI AG 2022-07-01
Series:Biomedicines
Subjects:
mitochondria
homeostasis
unfolded protein response
proteostasis
therapeutic target
mitochondrial diseases
Online Access:https://www.mdpi.com/2227-9059/10/7/1611

Internet

https://www.mdpi.com/2227-9059/10/7/1611

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