Impact of antigenic evolution and original antigenic sin on SARS-CoV-2 immunity

Impact of antigenic evolution and original antigenic sin on SARS-CoV-2 immunity

Infections with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) and vaccinations targeting the spike protein (S) offer protective immunity against coronavirus disease 2019 (COVID-19). This immunity may further be shaped by cross-reactivity with common cold coronaviruses. Mutations arisi...

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Bibliographic Details
Main Authors: Muriel Aguilar-Bretones, Ron A.M. Fouchier, Marion P.G. Koopmans, Gijsbert P. van Nierop
Format: Article
Language:English
Published: American Society for Clinical Investigation 2023-01-01
Series:The Journal of Clinical Investigation
Online Access:https://doi.org/10.1172/JCI162192

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