Trend of prevalence and incidence of systemic lupus erythematosus in South Korea, 2005 to 2015: a nationwide population-based study
Background/Aims The aim of this study was to evaluate the trend of incidence and prevalence of systemic lupus erythematosus (SLE) in South Korea from 2005 to 2015. Methods From 2005 to 2015, individuals with SLE were identified from the National Health Insurance database, which records information o...
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| Format: | Article |
| Language: | English |
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The Korean Association of Internal Medicine
2020-05-01
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| Series: | The Korean Journal of Internal Medicine |
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| Online Access: | http://www.kjim.org/upload/pdf/kjim-2018-303.pdf |
| _version_ | 1819123283220496384 |
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| author | Eun Hui Bae Sang Yeob Lim Kyung-Do Han Jin-Hyung Jung Hong Sang Choi Ha Yeon Kim Chang Seong Kim Seong Kwon Ma Soo Wan Kim |
| author_facet | Eun Hui Bae Sang Yeob Lim Kyung-Do Han Jin-Hyung Jung Hong Sang Choi Ha Yeon Kim Chang Seong Kim Seong Kwon Ma Soo Wan Kim |
| author_sort | Eun Hui Bae |
| collection | DOAJ |
| description | Background/Aims The aim of this study was to evaluate the trend of incidence and prevalence of systemic lupus erythematosus (SLE) in South Korea from 2005 to 2015. Methods From 2005 to 2015, individuals with SLE were identified from the National Health Insurance database, which records information on almost all Koreans. SLE was defined according to the International Classification of Diseases, 10th revision (ICD-10), code M32. The incidence was calculated per 100,000 person-years. The prevalence was calculated per 100,000 people and stratified by year, age group, sex, region, and income. Results The annual prevalence of SLE increased slightly from 21.25/100,000 people in 2005 to 35.45/100,000 people in 2015. In contrast, the annual incidence of SLE decreased slightly from 5.42/100,000 person-years in 2005 to 3.6/100,000 person-years in 2015. The prevalence and incidence of SLE were 10- and 6-fold higher in women than in men, respectively. The peak age of prevalence and incidence was 30 to 39 years in 2005; in 2015, the peak age of prevalence was 30 to 49 years and of incidence was 20 to 49 years. Regional variation was observed in both incidence and prevalence of SLE. Jeju province showed the highest prevalence of SLE (44.54/100,000 person-years), and Gwangju province showed the highest incidence of SLE (6.98/100,000 person-years) in 2015. The income status did not affect the prevalence or incidence of SLE except in patients without income who received medical aid. Conclusions The incidence of SLE has declined, but the prevalence has increased in Korea in recent years. Peak age of SLE trend to right shift in Korea. |
| first_indexed | 2024-12-22T07:05:53Z |
| format | Article |
| id | doaj.art-429732f33c6b4278a182da070112409c |
| institution | Directory Open Access Journal |
| issn | 1226-3303 2005-6648 |
| language | English |
| last_indexed | 2024-12-22T07:05:53Z |
| publishDate | 2020-05-01 |
| publisher | The Korean Association of Internal Medicine |
| record_format | Article |
| series | The Korean Journal of Internal Medicine |
| spelling | doaj.art-429732f33c6b4278a182da070112409c2022-12-21T18:34:41ZengThe Korean Association of Internal MedicineThe Korean Journal of Internal Medicine1226-33032005-66482020-05-0135365266110.3904/kjim.2018.303170208Trend of prevalence and incidence of systemic lupus erythematosus in South Korea, 2005 to 2015: a nationwide population-based studyEun Hui Bae0Sang Yeob Lim1Kyung-Do Han2Jin-Hyung Jung3Hong Sang Choi4Ha Yeon Kim5Chang Seong Kim6Seong Kwon Ma7Soo Wan Kim8 Department of Internal Medicine, Chonnam National University Medical School, Gwangju, Korea Department of Internal Medicine, Korea University Ansan Hospital, Ansan, Korea Department of Medical Statistics, College of Medicine, The Catholic University of Korea, Seoul, Korea Department of Medical Statistics, College of Medicine, The Catholic University of Korea, Seoul, Korea Department of Internal Medicine, Chonnam National University Medical School, Gwangju, Korea Department of Internal Medicine, Chonnam National University Medical School, Gwangju, Korea Department of Internal Medicine, Chonnam National University Medical School, Gwangju, Korea Department of Internal Medicine, Chonnam National University Medical School, Gwangju, Korea Department of Internal Medicine, Chonnam National University Medical School, Gwangju, KoreaBackground/Aims The aim of this study was to evaluate the trend of incidence and prevalence of systemic lupus erythematosus (SLE) in South Korea from 2005 to 2015. Methods From 2005 to 2015, individuals with SLE were identified from the National Health Insurance database, which records information on almost all Koreans. SLE was defined according to the International Classification of Diseases, 10th revision (ICD-10), code M32. The incidence was calculated per 100,000 person-years. The prevalence was calculated per 100,000 people and stratified by year, age group, sex, region, and income. Results The annual prevalence of SLE increased slightly from 21.25/100,000 people in 2005 to 35.45/100,000 people in 2015. In contrast, the annual incidence of SLE decreased slightly from 5.42/100,000 person-years in 2005 to 3.6/100,000 person-years in 2015. The prevalence and incidence of SLE were 10- and 6-fold higher in women than in men, respectively. The peak age of prevalence and incidence was 30 to 39 years in 2005; in 2015, the peak age of prevalence was 30 to 49 years and of incidence was 20 to 49 years. Regional variation was observed in both incidence and prevalence of SLE. Jeju province showed the highest prevalence of SLE (44.54/100,000 person-years), and Gwangju province showed the highest incidence of SLE (6.98/100,000 person-years) in 2015. The income status did not affect the prevalence or incidence of SLE except in patients without income who received medical aid. Conclusions The incidence of SLE has declined, but the prevalence has increased in Korea in recent years. Peak age of SLE trend to right shift in Korea.http://www.kjim.org/upload/pdf/kjim-2018-303.pdflupus erythematosus, systemicprevalenceincidencedatabasekorea |
| spellingShingle | Eun Hui Bae Sang Yeob Lim Kyung-Do Han Jin-Hyung Jung Hong Sang Choi Ha Yeon Kim Chang Seong Kim Seong Kwon Ma Soo Wan Kim Trend of prevalence and incidence of systemic lupus erythematosus in South Korea, 2005 to 2015: a nationwide population-based study The Korean Journal of Internal Medicine lupus erythematosus, systemic prevalence incidence database korea |
| title | Trend of prevalence and incidence of systemic lupus erythematosus in South Korea, 2005 to 2015: a nationwide population-based study |
| title_full | Trend of prevalence and incidence of systemic lupus erythematosus in South Korea, 2005 to 2015: a nationwide population-based study |
| title_fullStr | Trend of prevalence and incidence of systemic lupus erythematosus in South Korea, 2005 to 2015: a nationwide population-based study |
| title_full_unstemmed | Trend of prevalence and incidence of systemic lupus erythematosus in South Korea, 2005 to 2015: a nationwide population-based study |
| title_short | Trend of prevalence and incidence of systemic lupus erythematosus in South Korea, 2005 to 2015: a nationwide population-based study |
| title_sort | trend of prevalence and incidence of systemic lupus erythematosus in south korea 2005 to 2015 a nationwide population based study |
| topic | lupus erythematosus, systemic prevalence incidence database korea |
| url | http://www.kjim.org/upload/pdf/kjim-2018-303.pdf |
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