Uncoupled embryonic and extra-embryonic tissues compromise blastocyst development after somatic cell nuclear transfer.

Uncoupled embryonic and extra-embryonic tissues compromise blastocyst development after somatic cell nuclear transfer.

Somatic cell nuclear transfer (SCNT) is the most efficient cell reprogramming technique available, especially when working with bovine species. Although SCNT blastocysts performed equally well or better than controls in the weeks following embryo transfer at Day 7, elongation and gastrulation defect...

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Bibliographic Details
Main Authors: Séverine A Degrelle, Florence Jaffrezic, Evelyne Campion, Kim-Anh Lê Cao, Daniel Le Bourhis, Christophe Richard, Nathalie Rodde, Renaud Fleurot, Robin E Everts, Jérôme Lecardonnel, Yvan Heyman, Xavier Vignon, Xiangzhong Yang, Xiuchun C Tian, Harris A Lewin, Jean-Paul Renard, Isabelle Hue
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3368877?pdf=render

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