Icariin-conditioned serum combined with chitosan attenuates cartilage injury in rabbit knees with osteochondral defect

Icariin-conditioned serum combined with chitosan attenuates cartilage injury in rabbit knees with osteochondral defect

Abstract Background Knee osteoarthritis (KOA) is one of the most common degenerative diseases. Its development is closely related to cartilage injury and subchondral bone remodeling homeostasis. In the present study, we combined icariin-conditioned serum (ICS) with thiolated chitosan (CSSH), a mater...

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Bibliographic Details
Main Authors: Juntao Zhang, Fangyang Fan, Chao Zhang, Aifeng Liu, Man Shang, Lin Meng
Format: Article
Language:English
Published: BMC 2023-02-01
Series:Journal of Orthopaedic Surgery and Research
Subjects:
Osteoarthritis
Icariin
Chitosan
Cartilage repair
Subchondral bone
Online Access:https://doi.org/10.1186/s13018-023-03607-w

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