Saudi coronary atherothrombosis intravascular ultra sound study in patients presenting with acute coronary syndromes
Clinical Research. Presentation type: Oral Presentation. Introduction: Cardiovascular disease is the leading cause of mortality in diabetic patients. Diabetes is associated with more severe coronary stenosis. The current study is the first in Saudi Arabia that aim to establish an intravascular ultra...
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| Format: | Article |
| Language: | English |
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Saudi Heart Association
2017-10-01
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| Series: | Journal of the Saudi Heart Association |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S1016731517300726 |
| _version_ | 1831687291061403648 |
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| author | Samih Lawand Sarah Albabtain |
| author_facet | Samih Lawand Sarah Albabtain |
| author_sort | Samih Lawand |
| collection | DOAJ |
| description | Clinical Research.
Presentation type: Oral Presentation.
Introduction: Cardiovascular disease is the leading cause of mortality in diabetic patients. Diabetes is associated with more severe coronary stenosis. The current study is the first in Saudi Arabia that aim to establish an intravascular ultrasound (IVUS) profile of diabetic mellitus (DM) patients with acute coronary syndrome.
Methodology: We retrospectively analysed 210 IVUS studies performed in 188 patients. All patients were hospitalized in King Salman Heart Center for acute coronary syndromes (ACS). The IVUS studies were carried out upon discretion of the operator to guide percutaneous interventions of borderline moderate lesions.
Results: Mean age was 57.8 ± 10.1 years, 78% (n = 163) were men and 71% (n = 128) were diabetics. STEMI was the most common clinical presentation (47.8%, n = 88). As compared to non-diabetics, the intermediate lesions of DM patients had a significantly larger IVUS plaque volume (267.4 ± 173.7 mm3 versus 193.1 ± 111.1 mm3 for non DM group, p < 0.001), larger vessel volume (495.9 ± 313.6 mm3 versus 358.2 ± 181.7 mm3, p < 0.001), larger lumen volume (231.2 ± 156.2 mm3 versus 163.5 ± 87.9 mm3, p < 0.001) and longer lesions (37.37 ± 12.25 mm versus 29.93 ± 8.43 mm, p = 0.004). Positive without a significant difference. Percent plaque volume and obstruction were however not different, as well as artery remodeling index.
Conclusion: Diabetic patients with ACS in Saudi Arabia have longer lesions to be treated by IVUS, but no difference in average plaque burden nor remodeling. These findings are likely to impact our understanding of the optimal percutaneous interventions for our diabetic patients. |
| first_indexed | 2024-12-20T08:55:37Z |
| format | Article |
| id | doaj.art-429bdfc9109c426695f9f0bed6ed13cd |
| institution | Directory Open Access Journal |
| issn | 1016-7315 |
| language | English |
| last_indexed | 2024-12-20T08:55:37Z |
| publishDate | 2017-10-01 |
| publisher | Saudi Heart Association |
| record_format | Article |
| series | Journal of the Saudi Heart Association |
| spelling | doaj.art-429bdfc9109c426695f9f0bed6ed13cd2022-12-21T19:46:01ZengSaudi Heart AssociationJournal of the Saudi Heart Association1016-73152017-10-0129431510.1016/j.jsha.2017.06.008Saudi coronary atherothrombosis intravascular ultra sound study in patients presenting with acute coronary syndromesSamih LawandSarah AlbabtainClinical Research. Presentation type: Oral Presentation. Introduction: Cardiovascular disease is the leading cause of mortality in diabetic patients. Diabetes is associated with more severe coronary stenosis. The current study is the first in Saudi Arabia that aim to establish an intravascular ultrasound (IVUS) profile of diabetic mellitus (DM) patients with acute coronary syndrome. Methodology: We retrospectively analysed 210 IVUS studies performed in 188 patients. All patients were hospitalized in King Salman Heart Center for acute coronary syndromes (ACS). The IVUS studies were carried out upon discretion of the operator to guide percutaneous interventions of borderline moderate lesions. Results: Mean age was 57.8 ± 10.1 years, 78% (n = 163) were men and 71% (n = 128) were diabetics. STEMI was the most common clinical presentation (47.8%, n = 88). As compared to non-diabetics, the intermediate lesions of DM patients had a significantly larger IVUS plaque volume (267.4 ± 173.7 mm3 versus 193.1 ± 111.1 mm3 for non DM group, p < 0.001), larger vessel volume (495.9 ± 313.6 mm3 versus 358.2 ± 181.7 mm3, p < 0.001), larger lumen volume (231.2 ± 156.2 mm3 versus 163.5 ± 87.9 mm3, p < 0.001) and longer lesions (37.37 ± 12.25 mm versus 29.93 ± 8.43 mm, p = 0.004). Positive without a significant difference. Percent plaque volume and obstruction were however not different, as well as artery remodeling index. Conclusion: Diabetic patients with ACS in Saudi Arabia have longer lesions to be treated by IVUS, but no difference in average plaque burden nor remodeling. These findings are likely to impact our understanding of the optimal percutaneous interventions for our diabetic patients.http://www.sciencedirect.com/science/article/pii/S1016731517300726 |
| spellingShingle | Samih Lawand Sarah Albabtain Saudi coronary atherothrombosis intravascular ultra sound study in patients presenting with acute coronary syndromes Journal of the Saudi Heart Association |
| title | Saudi coronary atherothrombosis intravascular ultra sound study in patients presenting with acute coronary syndromes |
| title_full | Saudi coronary atherothrombosis intravascular ultra sound study in patients presenting with acute coronary syndromes |
| title_fullStr | Saudi coronary atherothrombosis intravascular ultra sound study in patients presenting with acute coronary syndromes |
| title_full_unstemmed | Saudi coronary atherothrombosis intravascular ultra sound study in patients presenting with acute coronary syndromes |
| title_short | Saudi coronary atherothrombosis intravascular ultra sound study in patients presenting with acute coronary syndromes |
| title_sort | saudi coronary atherothrombosis intravascular ultra sound study in patients presenting with acute coronary syndromes |
| url | http://www.sciencedirect.com/science/article/pii/S1016731517300726 |
| work_keys_str_mv | AT samihlawand saudicoronaryatherothrombosisintravascularultrasoundstudyinpatientspresentingwithacutecoronarysyndromes AT sarahalbabtain saudicoronaryatherothrombosisintravascularultrasoundstudyinpatientspresentingwithacutecoronarysyndromes |