HLA-associated protection of lymphocytes during influenza virus infection

HLA-associated protection of lymphocytes during influenza virus infection

Abstract Background Heterozygosity at HLA class I loci is generally considered beneficial for host defense. We report here an element of HLA class I homozygosity that may or may not help preserve its existence in populations but which could indicate a new avenue for antiviral research. Methods Lymph...

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Bibliographic Details
Main Authors: Eliana E. Ochoa, Ruksana Huda, Steven F. Scheibel, Joan E. Nichols, David J. Mock, Nayef El-Daher, Frank M. Domurat, Norbert J. Roberts
Format: Article
Language:English
Published: BMC 2020-08-01
Series:Virology Journal
Subjects:
HLA
Human leukocyte antigen
Influenza virus
Human lymphocytes
Homozygosity
Monocytes/macrophages
Online Access:http://link.springer.com/article/10.1186/s12985-020-01406-x

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