Microglia activation is essential for BMP7-mediated retinal reactive gliosis

Microglia activation is essential for BMP7-mediated retinal reactive gliosis

Abstract Background Our previous studies have shown that BMP7 is able to trigger activation of retinal macroglia. However, these studies showed the responsiveness of Müller glial cells and retinal astrocytes in vitro was attenuated in comparison to those in vivo, indicating other retinal cell types...

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Bibliographic Details
Main Authors: Subramanian Dharmarajan, Debra L. Fisk, Christine M. Sorenson, Nader Sheibani, Teri L. Belecky-Adams
Format: Article
Language:English
Published: BMC 2017-04-01
Series:Journal of Neuroinflammation
Subjects:
Microglia
Reactive gliosis
BMP7
Retina
Müller glia
Retinal astrocytes
Online Access:http://link.springer.com/article/10.1186/s12974-017-0855-0

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