Early Detection of Atrial Fibrillation in Community Pharmacies—CRIFAFARMA Study

Background: Atrial fibrillation (AF) is the most common arrhythmia to appear in clinical practice. People with AF have 5 times the risk of stroke compared to the general population. Objective: This study aimed to determine the prevalence of AF in people over the age of 50 without known AF, who prese...

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Main Authors: María González Valdivieso PhD, Domingo Orozco-Beltrán MD, PhD, Adriana López-Pineda PhD, Vicente Francisco Gil-Guillén MD, PhD, José A. Quesada PhD, Concepción Carratalá-Munuera PhD, Rauf Nouni-García PhD
Format: Article
Language:English
Published: SAGE Publishing 2022-02-01
Series:Journal of Cardiovascular Pharmacology and Therapeutics
Online Access:https://doi.org/10.1177/10742484221078973
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author María González Valdivieso PhD
Domingo Orozco-Beltrán MD, PhD
Adriana López-Pineda PhD
Vicente Francisco Gil-Guillén MD, PhD
José A. Quesada PhD
Concepción Carratalá-Munuera PhD
Rauf Nouni-García PhD
author_facet María González Valdivieso PhD
Domingo Orozco-Beltrán MD, PhD
Adriana López-Pineda PhD
Vicente Francisco Gil-Guillén MD, PhD
José A. Quesada PhD
Concepción Carratalá-Munuera PhD
Rauf Nouni-García PhD
author_sort María González Valdivieso PhD
collection DOAJ
description Background: Atrial fibrillation (AF) is the most common arrhythmia to appear in clinical practice. People with AF have 5 times the risk of stroke compared to the general population. Objective: This study aimed to determine the prevalence of AF in people over the age of 50 without known AF, who presented to a community pharmacy to check their cardiovascular risk factors, to identify risk factors associated with AF, and to assess the risk of stroke in people who screened positive for AF. Methods: A multicenter observational descriptive study of a screening program took place from May to December 2016. A blood pressure monitor (Microlife Watch BP Home) was used to screen for AF, and the CHA2DS2-VASc questionnaire was used to assess stroke risk. Results: The study included 452 adults over the age of 50. The CRIFAFARMA study detected a prevalence of AF of 9.1%. Risk factors for AF were: age of 75 years or older ( P = .024), lack of physical activity ( P = .043), diabetes ( P < .001), dyslipidemia ( P = .003), and history of cardiovascular disease ( P = .003). Diabetes (OR 2.79, P = .005) and dyslipidemia (OR 2.16, P = .031) had a combined explanatory capacity in the multivariable logistic regression model adjusted for age. 85% were at high risk of stroke according to the CHA2DS2-VASc scale. Conclusions: AF was detected in more than 9% of the included population. Factors associated with AF were advanced age, lack of physical activity, diabetes, dyslipidemia, and history of cardiovascular disease, with diabetes and dyslipidemia standing out as the factors with independent explanatory capacity.
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spelling doaj.art-42a89ec822f948c3bd6df8090f76c6772022-12-22T02:40:38ZengSAGE PublishingJournal of Cardiovascular Pharmacology and Therapeutics1940-40342022-02-012710.1177/10742484221078973Early Detection of Atrial Fibrillation in Community Pharmacies—CRIFAFARMA StudyMaría González Valdivieso PhD0Domingo Orozco-Beltrán MD, PhD1Adriana López-Pineda PhD2Vicente Francisco Gil-Guillén MD, PhD3José A. Quesada PhD4Concepción Carratalá-Munuera PhD5Rauf Nouni-García PhD6 Department of Clinical Medicine, , San Juan de Alicante, Spain Department of Clinical Medicine, , San Juan de Alicante, Spain Department of Clinical Medicine, , San Juan de Alicante, Spain Department of Clinical Medicine, , San Juan de Alicante, Spain Department of Clinical Medicine, , San Juan de Alicante, Spain Department of Clinical Medicine, , San Juan de Alicante, Spain Department of Clinical Medicine, , San Juan de Alicante, SpainBackground: Atrial fibrillation (AF) is the most common arrhythmia to appear in clinical practice. People with AF have 5 times the risk of stroke compared to the general population. Objective: This study aimed to determine the prevalence of AF in people over the age of 50 without known AF, who presented to a community pharmacy to check their cardiovascular risk factors, to identify risk factors associated with AF, and to assess the risk of stroke in people who screened positive for AF. Methods: A multicenter observational descriptive study of a screening program took place from May to December 2016. A blood pressure monitor (Microlife Watch BP Home) was used to screen for AF, and the CHA2DS2-VASc questionnaire was used to assess stroke risk. Results: The study included 452 adults over the age of 50. The CRIFAFARMA study detected a prevalence of AF of 9.1%. Risk factors for AF were: age of 75 years or older ( P = .024), lack of physical activity ( P = .043), diabetes ( P < .001), dyslipidemia ( P = .003), and history of cardiovascular disease ( P = .003). Diabetes (OR 2.79, P = .005) and dyslipidemia (OR 2.16, P = .031) had a combined explanatory capacity in the multivariable logistic regression model adjusted for age. 85% were at high risk of stroke according to the CHA2DS2-VASc scale. Conclusions: AF was detected in more than 9% of the included population. Factors associated with AF were advanced age, lack of physical activity, diabetes, dyslipidemia, and history of cardiovascular disease, with diabetes and dyslipidemia standing out as the factors with independent explanatory capacity.https://doi.org/10.1177/10742484221078973
spellingShingle María González Valdivieso PhD
Domingo Orozco-Beltrán MD, PhD
Adriana López-Pineda PhD
Vicente Francisco Gil-Guillén MD, PhD
José A. Quesada PhD
Concepción Carratalá-Munuera PhD
Rauf Nouni-García PhD
Early Detection of Atrial Fibrillation in Community Pharmacies—CRIFAFARMA Study
Journal of Cardiovascular Pharmacology and Therapeutics
title Early Detection of Atrial Fibrillation in Community Pharmacies—CRIFAFARMA Study
title_full Early Detection of Atrial Fibrillation in Community Pharmacies—CRIFAFARMA Study
title_fullStr Early Detection of Atrial Fibrillation in Community Pharmacies—CRIFAFARMA Study
title_full_unstemmed Early Detection of Atrial Fibrillation in Community Pharmacies—CRIFAFARMA Study
title_short Early Detection of Atrial Fibrillation in Community Pharmacies—CRIFAFARMA Study
title_sort early detection of atrial fibrillation in community pharmacies crifafarma study
url https://doi.org/10.1177/10742484221078973
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