Integrated proteomic and transcriptomic landscape of macrophages in mouse tissues
Macrophage is located in different tissue to serve diverse functions. Here the authors use mass spectrometry and bulk RNA-sequencing to profile 11 mouse macrophage populations from 8 tissues, and combine their de novo data with public datasets to report an integrated proteomic and transcriptomic lan...
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Format: | Article |
Language: | English |
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Nature Portfolio
2022-11-01
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Series: | Nature Communications |
Online Access: | https://doi.org/10.1038/s41467-022-35095-7 |
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author | Jingbo Qie Yang Liu Yunzhi Wang Fan Zhang Zhaoyu Qin Sha Tian Mingwei Liu Kai Li Wenhao Shi Lei Song Mingjun Sun Yexin Tong Ping Hu Tao Gong Xiaqiong Wang Yi Huang Bolong Lin Xuesen Zheng Rongbin Zhou Jie Lv Changsheng Du Yi Wang Jun Qin Wenjun Yang Fuchu He Chen Ding |
author_facet | Jingbo Qie Yang Liu Yunzhi Wang Fan Zhang Zhaoyu Qin Sha Tian Mingwei Liu Kai Li Wenhao Shi Lei Song Mingjun Sun Yexin Tong Ping Hu Tao Gong Xiaqiong Wang Yi Huang Bolong Lin Xuesen Zheng Rongbin Zhou Jie Lv Changsheng Du Yi Wang Jun Qin Wenjun Yang Fuchu He Chen Ding |
author_sort | Jingbo Qie |
collection | DOAJ |
description | Macrophage is located in different tissue to serve diverse functions. Here the authors use mass spectrometry and bulk RNA-sequencing to profile 11 mouse macrophage populations from 8 tissues, and combine their de novo data with public datasets to report an integrated proteomic and transcriptomic landscape of mouse macrophage as a valuable resource. |
first_indexed | 2024-04-12T04:08:23Z |
format | Article |
id | doaj.art-42aa5c3f294d4fc78c544a437d316019 |
institution | Directory Open Access Journal |
issn | 2041-1723 |
language | English |
last_indexed | 2024-04-12T04:08:23Z |
publishDate | 2022-11-01 |
publisher | Nature Portfolio |
record_format | Article |
series | Nature Communications |
spelling | doaj.art-42aa5c3f294d4fc78c544a437d3160192022-12-22T03:48:34ZengNature PortfolioNature Communications2041-17232022-11-0113112310.1038/s41467-022-35095-7Integrated proteomic and transcriptomic landscape of macrophages in mouse tissuesJingbo Qie0Yang Liu1Yunzhi Wang2Fan Zhang3Zhaoyu Qin4Sha Tian5Mingwei Liu6Kai Li7Wenhao Shi8Lei Song9Mingjun Sun10Yexin Tong11Ping Hu12Tao Gong13Xiaqiong Wang14Yi Huang15Bolong Lin16Xuesen Zheng17Rongbin Zhou18Jie Lv19Changsheng Du20Yi Wang21Jun Qin22Wenjun Yang23Fuchu He24Chen Ding25State Key Laboratory of Genetic Engineering, Institutes of Biomedical Sciences, Human Phenome Institute, School of Life Sciences, Zhongshan Hospital, Fudan UniversityState Key Laboratory of Genetic Engineering, Institutes of Biomedical Sciences, Human Phenome Institute, School of Life Sciences, Zhongshan Hospital, Fudan UniversityState Key Laboratory of Genetic Engineering, Institutes of Biomedical Sciences, Human Phenome Institute, School of Life Sciences, Zhongshan Hospital, Fudan UniversityState Key Laboratory of Genetic Engineering, Institutes of Biomedical Sciences, Human Phenome Institute, School of Life Sciences, Zhongshan Hospital, Fudan UniversityState Key Laboratory of Genetic Engineering, Institutes of Biomedical Sciences, Human Phenome Institute, School of Life Sciences, Zhongshan Hospital, Fudan UniversityState Key Laboratory of Genetic Engineering, Institutes of Biomedical Sciences, Human Phenome Institute, School of Life Sciences, Zhongshan Hospital, Fudan UniversityState Key Laboratory of Proteomics, Beijing Proteome Research Center, National Center for Protein SciencesState Key Laboratory of Proteomics, Beijing Proteome Research Center, National Center for Protein SciencesState Key Laboratory of Proteomics, Beijing Proteome Research Center, National Center for Protein SciencesState Key Laboratory of Proteomics, Beijing Proteome Research Center, National Center for Protein SciencesState Key Laboratory of Genetic Engineering, Institutes of Biomedical Sciences, Human Phenome Institute, School of Life Sciences, Zhongshan Hospital, Fudan UniversityState Key Laboratory of Genetic Engineering, Institutes of Biomedical Sciences, Human Phenome Institute, School of Life Sciences, Zhongshan Hospital, Fudan UniversityDepartment of Pediatric Orthopedics, Xin Hua Hospital Affiliated to Shanghai Jiao Tong University, School of MedicineHefei National Laboratory for Physical Sciences at Microscale, The CAS Key Laboratory of Innate Immunity and Chronic Disease, School of Life Sciences, University of Science and Technology of ChinaHefei National Laboratory for Physical Sciences at Microscale, The CAS Key Laboratory of Innate Immunity and Chronic Disease, School of Life Sciences, University of Science and Technology of ChinaHefei National Laboratory for Physical Sciences at Microscale, The CAS Key Laboratory of Innate Immunity and Chronic Disease, School of Life Sciences, University of Science and Technology of ChinaHefei National Laboratory for Physical Sciences at Microscale, The CAS Key Laboratory of Innate Immunity and Chronic Disease, School of Life Sciences, University of Science and Technology of ChinaHefei National Laboratory for Physical Sciences at Microscale, The CAS Key Laboratory of Innate Immunity and Chronic Disease, School of Life Sciences, University of Science and Technology of ChinaHefei National Laboratory for Physical Sciences at Microscale, The CAS Key Laboratory of Innate Immunity and Chronic Disease, School of Life Sciences, University of Science and Technology of ChinaPutuo District People’s Hospital, Shanghai Key Laboratory of Signaling and Disease Research, School of Life Sciences and Technology, Tongji UniversityPutuo District People’s Hospital, Shanghai Key Laboratory of Signaling and Disease Research, School of Life Sciences and Technology, Tongji UniversityState Key Laboratory of Proteomics, Beijing Proteome Research Center, National Center for Protein SciencesState Key Laboratory of Genetic Engineering, Institutes of Biomedical Sciences, Human Phenome Institute, School of Life Sciences, Zhongshan Hospital, Fudan UniversityDepartment of Pediatric Orthopedics, Xin Hua Hospital Affiliated to Shanghai Jiao Tong University, School of MedicineState Key Laboratory of Genetic Engineering, Institutes of Biomedical Sciences, Human Phenome Institute, School of Life Sciences, Zhongshan Hospital, Fudan UniversityState Key Laboratory of Genetic Engineering, Institutes of Biomedical Sciences, Human Phenome Institute, School of Life Sciences, Zhongshan Hospital, Fudan UniversityMacrophage is located in different tissue to serve diverse functions. Here the authors use mass spectrometry and bulk RNA-sequencing to profile 11 mouse macrophage populations from 8 tissues, and combine their de novo data with public datasets to report an integrated proteomic and transcriptomic landscape of mouse macrophage as a valuable resource.https://doi.org/10.1038/s41467-022-35095-7 |
spellingShingle | Jingbo Qie Yang Liu Yunzhi Wang Fan Zhang Zhaoyu Qin Sha Tian Mingwei Liu Kai Li Wenhao Shi Lei Song Mingjun Sun Yexin Tong Ping Hu Tao Gong Xiaqiong Wang Yi Huang Bolong Lin Xuesen Zheng Rongbin Zhou Jie Lv Changsheng Du Yi Wang Jun Qin Wenjun Yang Fuchu He Chen Ding Integrated proteomic and transcriptomic landscape of macrophages in mouse tissues Nature Communications |
title | Integrated proteomic and transcriptomic landscape of macrophages in mouse tissues |
title_full | Integrated proteomic and transcriptomic landscape of macrophages in mouse tissues |
title_fullStr | Integrated proteomic and transcriptomic landscape of macrophages in mouse tissues |
title_full_unstemmed | Integrated proteomic and transcriptomic landscape of macrophages in mouse tissues |
title_short | Integrated proteomic and transcriptomic landscape of macrophages in mouse tissues |
title_sort | integrated proteomic and transcriptomic landscape of macrophages in mouse tissues |
url | https://doi.org/10.1038/s41467-022-35095-7 |
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