Altered glucose homeostasis and hepatic function in obese mice deficient for both kinin receptor genes.

Altered glucose homeostasis and hepatic function in obese mice deficient for both kinin receptor genes.

The Kallikrein-Kinin System (KKS) has been implicated in several aspects of metabolism, including the regulation of glucose homeostasis and adiposity. Kinins and des-Arg-kinins are the major effectors of this system and promote their effects by binding to two different receptors, the kinin B2 and B1...

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Main Authors: Carlos C Barros, Anderson Haro, Fernanda J V P Russo, Ines Schadock, Sandro S Almeida, Rosane A Ribeiro, Emerielle C Vanzela, Valeria P Lanzoni, Flavio C Barros, Milton R Moraes, Marcelo A Mori, Reury F P Bacurau, Martin Wurtele, Antônio C Boschero, Everardo M Carneiro, Michael Bader, Joao B Pesquero, Ronaldo C Araujo
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3400662?pdf=render

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