Minireview: Prospect of Doxycycline in Systemic Lupus Erythematosus Treatment

Doxycycline has non-antibiotic effects which are necessary for lupus treatment, such as immunosuppressive, anti-inflammatory, and anti-depressive effects. This widely used drug is a promising one to be developed as lupus drug since doxycycline has no data of its microbial resistance and it is safe...

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Main Authors: Niken Indriyanti, Joewono Soeroso
Format: Article
Language:English
Published: Mulawarman University 2019-06-01
Series:Journal of Tropical Pharmacy and Chemistry
Subjects:
Online Access:https://jtpc.farmasi.unmul.ac.id/index.php/jtpc/article/view/173
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author Niken Indriyanti
Joewono Soeroso
author_facet Niken Indriyanti
Joewono Soeroso
author_sort Niken Indriyanti
collection DOAJ
description Doxycycline has non-antibiotic effects which are necessary for lupus treatment, such as immunosuppressive, anti-inflammatory, and anti-depressive effects. This widely used drug is a promising one to be developed as lupus drug since doxycycline has no data of its microbial resistance and it is safe for maternity. The other benefit is that doxycycline has lower side effects than the current drugs for lupus treatment. It gives excellent chances for women with lupus to be pregnant and have healthy babies. This article contains the compilation data of doxycycline target sites beyond its beneficial activities for lupus and also its limitations. Finally, this data will be a background for doxycycline in lupus drug development.
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spelling doaj.art-42ab752ddc6c47cfa8c559d3746058132023-11-04T06:12:00ZengMulawarman UniversityJournal of Tropical Pharmacy and Chemistry2087-70992407-60902019-06-014510.25026/jtpc.v4i5.173Minireview: Prospect of Doxycycline in Systemic Lupus Erythematosus TreatmentNiken Indriyanti0Joewono Soeroso1Fakultas Farmasi, Mulawarman University, Samarinda, IndonesiaDepartment of Internal Medicine, Faculty of Medicine, Universitas Airlangga, Surabaya, East Java, Indonesia Doxycycline has non-antibiotic effects which are necessary for lupus treatment, such as immunosuppressive, anti-inflammatory, and anti-depressive effects. This widely used drug is a promising one to be developed as lupus drug since doxycycline has no data of its microbial resistance and it is safe for maternity. The other benefit is that doxycycline has lower side effects than the current drugs for lupus treatment. It gives excellent chances for women with lupus to be pregnant and have healthy babies. This article contains the compilation data of doxycycline target sites beyond its beneficial activities for lupus and also its limitations. Finally, this data will be a background for doxycycline in lupus drug development. https://jtpc.farmasi.unmul.ac.id/index.php/jtpc/article/view/173doxycyclinenon-antibiotic effectsmaternitylupusdrug development
spellingShingle Niken Indriyanti
Joewono Soeroso
Minireview: Prospect of Doxycycline in Systemic Lupus Erythematosus Treatment
Journal of Tropical Pharmacy and Chemistry
doxycycline
non-antibiotic effects
maternity
lupus
drug development
title Minireview: Prospect of Doxycycline in Systemic Lupus Erythematosus Treatment
title_full Minireview: Prospect of Doxycycline in Systemic Lupus Erythematosus Treatment
title_fullStr Minireview: Prospect of Doxycycline in Systemic Lupus Erythematosus Treatment
title_full_unstemmed Minireview: Prospect of Doxycycline in Systemic Lupus Erythematosus Treatment
title_short Minireview: Prospect of Doxycycline in Systemic Lupus Erythematosus Treatment
title_sort minireview prospect of doxycycline in systemic lupus erythematosus treatment
topic doxycycline
non-antibiotic effects
maternity
lupus
drug development
url https://jtpc.farmasi.unmul.ac.id/index.php/jtpc/article/view/173
work_keys_str_mv AT nikenindriyanti minireviewprospectofdoxycyclineinsystemiclupuserythematosustreatment
AT joewonosoeroso minireviewprospectofdoxycyclineinsystemiclupuserythematosustreatment