Pellagra as a potential complication of anorexia nervosa: A comprehensive literature review
Pellagra, a deficiency of niacin (Vitamin B3), is a potential secondary complication of anorexia nervosa (AN) resulting from restricted nutrient consumption. Symptoms observed in patients with pellagra (such as diarrhea, dermatitis, dementia, and death) can often overlap with or be affected by AN st...
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| Format: | Article |
| Language: | English |
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Elsevier
2023-06-01
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| Series: | Human Nutrition & Metabolism |
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| Online Access: | http://www.sciencedirect.com/science/article/pii/S2666149723000142 |
| _version_ | 1797820568791154688 |
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| author | Manu Onteeru |
| author_facet | Manu Onteeru |
| author_sort | Manu Onteeru |
| collection | DOAJ |
| description | Pellagra, a deficiency of niacin (Vitamin B3), is a potential secondary complication of anorexia nervosa (AN) resulting from restricted nutrient consumption. Symptoms observed in patients with pellagra (such as diarrhea, dermatitis, dementia, and death) can often overlap with or be affected by AN status. This article presents the largest literature review to date on symptoms observed with AN-induced pellagra, treatment regimens, and patient outcomes. An English literature search was performed using the keywords “pellagra” and “anorexia”, yielding seven female case reports. The most prevalent symptom (100%) reported was erythema of the face, neck, and arm regions. Symptoms traditionally associated with pellagra were not identified as frequently, such as diarrhea (29%). The most common treatment regime included both Vitamin B supplementation and dietary advice (83%), with all patients recorded recovering from pellagra. AN and pellagra may affect the symptomatic presentation of its counterpart disease, providing a challenge to practitioners tasked with diagnosing patients. Future studies are needed to clarify the symptomatic development of the diseases concurrently, and best practices in treatment and diagnosis. |
| first_indexed | 2024-03-13T09:40:19Z |
| format | Article |
| id | doaj.art-42acc8862c734ad6bef8bf8df8e8f08a |
| institution | Directory Open Access Journal |
| issn | 2666-1497 |
| language | English |
| last_indexed | 2024-03-13T09:40:19Z |
| publishDate | 2023-06-01 |
| publisher | Elsevier |
| record_format | Article |
| series | Human Nutrition & Metabolism |
| spelling | doaj.art-42acc8862c734ad6bef8bf8df8e8f08a2023-05-25T04:25:06ZengElsevierHuman Nutrition & Metabolism2666-14972023-06-0132200197Pellagra as a potential complication of anorexia nervosa: A comprehensive literature reviewManu Onteeru0Dartmouth College, Department of Biology, 15 Dewey Field Rd, Hanover, NH, 03755, USA.; Department of Biology, Dartmouth College, Hanover, NH, USAPellagra, a deficiency of niacin (Vitamin B3), is a potential secondary complication of anorexia nervosa (AN) resulting from restricted nutrient consumption. Symptoms observed in patients with pellagra (such as diarrhea, dermatitis, dementia, and death) can often overlap with or be affected by AN status. This article presents the largest literature review to date on symptoms observed with AN-induced pellagra, treatment regimens, and patient outcomes. An English literature search was performed using the keywords “pellagra” and “anorexia”, yielding seven female case reports. The most prevalent symptom (100%) reported was erythema of the face, neck, and arm regions. Symptoms traditionally associated with pellagra were not identified as frequently, such as diarrhea (29%). The most common treatment regime included both Vitamin B supplementation and dietary advice (83%), with all patients recorded recovering from pellagra. AN and pellagra may affect the symptomatic presentation of its counterpart disease, providing a challenge to practitioners tasked with diagnosing patients. Future studies are needed to clarify the symptomatic development of the diseases concurrently, and best practices in treatment and diagnosis.http://www.sciencedirect.com/science/article/pii/S2666149723000142Anorexia nervosaPellagraEating disorderDermatologyVitamin B |
| spellingShingle | Manu Onteeru Pellagra as a potential complication of anorexia nervosa: A comprehensive literature review Human Nutrition & Metabolism Anorexia nervosa Pellagra Eating disorder Dermatology Vitamin B |
| title | Pellagra as a potential complication of anorexia nervosa: A comprehensive literature review |
| title_full | Pellagra as a potential complication of anorexia nervosa: A comprehensive literature review |
| title_fullStr | Pellagra as a potential complication of anorexia nervosa: A comprehensive literature review |
| title_full_unstemmed | Pellagra as a potential complication of anorexia nervosa: A comprehensive literature review |
| title_short | Pellagra as a potential complication of anorexia nervosa: A comprehensive literature review |
| title_sort | pellagra as a potential complication of anorexia nervosa a comprehensive literature review |
| topic | Anorexia nervosa Pellagra Eating disorder Dermatology Vitamin B |
| url | http://www.sciencedirect.com/science/article/pii/S2666149723000142 |
| work_keys_str_mv | AT manuonteeru pellagraasapotentialcomplicationofanorexianervosaacomprehensiveliteraturereview |