Gynecomastia as Unusual Presentation of Primary Choriocarcinoma of the Colon: A Case Report and Literature Review
ABSTRACT: Objective: Gynecomastia is the benign enlargement of male breast tissue and is the most common breast condition in males. Beta human chorionic gonadotropin (β-hCG)-secreting tumors such as choriocarcinoma are one cause of gynecomastia. This is the first report of bilateral gynecomastia sec...
| Main Authors: | , , , , , |
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| Format: | Article |
| Language: | English |
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Elsevier
2015-01-01
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| Series: | AACE Clinical Case Reports |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S2376060520303424 |
| _version_ | 1831585009704632320 |
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| author | Maríaresa Te Julián, MD Eduarda Pizarro, MD, PhD Susana Martínez Peralta, MD Olga García Vidal, MD Sonia Casals, MD Enric Ballestar, MD |
| author_facet | Maríaresa Te Julián, MD Eduarda Pizarro, MD, PhD Susana Martínez Peralta, MD Olga García Vidal, MD Sonia Casals, MD Enric Ballestar, MD |
| author_sort | Maríaresa Te Julián, MD |
| collection | DOAJ |
| description | ABSTRACT: Objective: Gynecomastia is the benign enlargement of male breast tissue and is the most common breast condition in males. Beta human chorionic gonadotropin (β-hCG)-secreting tumors such as choriocarcinoma are one cause of gynecomastia. This is the first report of bilateral gynecomastia secondary to malignant β-hCG-secreting choriocarcinoma located in the colon.Methods: A 49 year-old male who presented bilateral gynecomastia was found to have a primary colonic choriocarcinoma.Results: Serum β-hCG levels were significantly high at 11.546 mIU/mL (normal range 0.01–5). A colonoscopy showed a stenosing mass in the sigmoid colon, and computed tomography revealed multiple liver metastases. The diagnosis of choriocarcinoma was confirmed by the histologic and immunohistochemical biopsy findings.Conclusion: Primary colorectal choriocarcinoma is a very rare entity that should be considered in the differential diagnosis of gynecomastia.Abbreviations: β-hCG human chorionic gonadotropin |
| first_indexed | 2024-12-17T21:09:36Z |
| format | Article |
| id | doaj.art-42ae9301aa37475d98a6a4c7d17df268 |
| institution | Directory Open Access Journal |
| issn | 2376-0605 |
| language | English |
| last_indexed | 2024-12-17T21:09:36Z |
| publishDate | 2015-01-01 |
| publisher | Elsevier |
| record_format | Article |
| series | AACE Clinical Case Reports |
| spelling | doaj.art-42ae9301aa37475d98a6a4c7d17df2682022-12-21T21:32:29ZengElsevierAACE Clinical Case Reports2376-06052015-01-0114e260e264Gynecomastia as Unusual Presentation of Primary Choriocarcinoma of the Colon: A Case Report and Literature ReviewMaríaresa Te Julián, MD0Eduarda Pizarro, MD, PhD1Susana Martínez Peralta, MD2Olga García Vidal, MD3Sonia Casals, MD4Enric Ballestar, MD5Department of Endocrinology, Hospital de Mataró, Barcelona, Spain.; Address correspondence to Dr. María Teresa Julián Alagarda; Department of Endocrinology, Hospital de Mataró; Carrer Prolongació Cirera s/n 08034 Mataró, Barcelona, Spain.Department of Endocrinology, Hospital de Mataró, Barcelona, Spain.Department of Oncology, Hospital de Mataró, Barcelona, Spain.Department of Pathology, Hospital de Mataró, Barcelona, Spain.Department of Radiology; Hospital de Mataró, Barcelona, Spain.Department of Endocrinology, Hospital de Mataró, Barcelona, Spain.ABSTRACT: Objective: Gynecomastia is the benign enlargement of male breast tissue and is the most common breast condition in males. Beta human chorionic gonadotropin (β-hCG)-secreting tumors such as choriocarcinoma are one cause of gynecomastia. This is the first report of bilateral gynecomastia secondary to malignant β-hCG-secreting choriocarcinoma located in the colon.Methods: A 49 year-old male who presented bilateral gynecomastia was found to have a primary colonic choriocarcinoma.Results: Serum β-hCG levels were significantly high at 11.546 mIU/mL (normal range 0.01–5). A colonoscopy showed a stenosing mass in the sigmoid colon, and computed tomography revealed multiple liver metastases. The diagnosis of choriocarcinoma was confirmed by the histologic and immunohistochemical biopsy findings.Conclusion: Primary colorectal choriocarcinoma is a very rare entity that should be considered in the differential diagnosis of gynecomastia.Abbreviations: β-hCG human chorionic gonadotropinhttp://www.sciencedirect.com/science/article/pii/S2376060520303424 |
| spellingShingle | Maríaresa Te Julián, MD Eduarda Pizarro, MD, PhD Susana Martínez Peralta, MD Olga García Vidal, MD Sonia Casals, MD Enric Ballestar, MD Gynecomastia as Unusual Presentation of Primary Choriocarcinoma of the Colon: A Case Report and Literature Review AACE Clinical Case Reports |
| title | Gynecomastia as Unusual Presentation of Primary Choriocarcinoma of the Colon: A Case Report and Literature Review |
| title_full | Gynecomastia as Unusual Presentation of Primary Choriocarcinoma of the Colon: A Case Report and Literature Review |
| title_fullStr | Gynecomastia as Unusual Presentation of Primary Choriocarcinoma of the Colon: A Case Report and Literature Review |
| title_full_unstemmed | Gynecomastia as Unusual Presentation of Primary Choriocarcinoma of the Colon: A Case Report and Literature Review |
| title_short | Gynecomastia as Unusual Presentation of Primary Choriocarcinoma of the Colon: A Case Report and Literature Review |
| title_sort | gynecomastia as unusual presentation of primary choriocarcinoma of the colon a case report and literature review |
| url | http://www.sciencedirect.com/science/article/pii/S2376060520303424 |
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