Dexamethasone intravitreal implant in cystoid macular edema secondary to paclitaxel therapy
Purpose: To report the first case of cystoid macular edema (CME) induced by nabpaclitaxel treated with intravitreal dexamethasone implant. Observations: A 67 year-old man diagnosed with unresectable pancreatic cancer presented with decreased vision in both eyes while receiving nab-paclitaxel. He was...
| Main Authors: | , , , |
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| Format: | Article |
| Language: | English |
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Elsevier
2020-06-01
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| Series: | American Journal of Ophthalmology Case Reports |
| Subjects: | |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S2451993620300347 |
| _version_ | 1818113291894915072 |
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| author | Barbara Burgos-Blasco Samuel Hernandez-Ruiz Lorenzo Lopez-Guajardo Juan Donate-Lopez |
| author_facet | Barbara Burgos-Blasco Samuel Hernandez-Ruiz Lorenzo Lopez-Guajardo Juan Donate-Lopez |
| author_sort | Barbara Burgos-Blasco |
| collection | DOAJ |
| description | Purpose: To report the first case of cystoid macular edema (CME) induced by nabpaclitaxel treated with intravitreal dexamethasone implant. Observations: A 67 year-old man diagnosed with unresectable pancreatic cancer presented with decreased vision in both eyes while receiving nab-paclitaxel. He was diagnosed with CME and intravitreal dexamethasone implants were administered in both eyes. Central retinal thickness (CRT) of both eye decreased 1 month after the implant but CME persisted. 2 months after Ozurdex implant nabpaclitaxel was discontinued, improving central macular thickness and the CME significantly in both eyes. Conclusion and importance: Cessation of nab-paclitaxel could lead to resolution of CME more than intravitreal dexamethasone implant, although intravitreal dexamethasone implant achieved some reduction in central macular thickness. |
| first_indexed | 2024-12-11T03:32:30Z |
| format | Article |
| id | doaj.art-42c2cbc229ea48829b215358e45f1c43 |
| institution | Directory Open Access Journal |
| issn | 2451-9936 |
| language | English |
| last_indexed | 2024-12-11T03:32:30Z |
| publishDate | 2020-06-01 |
| publisher | Elsevier |
| record_format | Article |
| series | American Journal of Ophthalmology Case Reports |
| spelling | doaj.art-42c2cbc229ea48829b215358e45f1c432022-12-22T01:22:21ZengElsevierAmerican Journal of Ophthalmology Case Reports2451-99362020-06-0118Dexamethasone intravitreal implant in cystoid macular edema secondary to paclitaxel therapyBarbara Burgos-Blasco0Samuel Hernandez-Ruiz1Lorenzo Lopez-Guajardo2Juan Donate-Lopez3Corresponding author. Hospital Clinico San Carlos, C/ Prof Martin Lagos s/n. 28040, Madrid, Spain.; Ophthalmology Department, Hospital Clinico San Carlos, Madrid, SpainOphthalmology Department, Hospital Clinico San Carlos, Madrid, SpainOphthalmology Department, Hospital Clinico San Carlos, Madrid, SpainOphthalmology Department, Hospital Clinico San Carlos, Madrid, SpainPurpose: To report the first case of cystoid macular edema (CME) induced by nabpaclitaxel treated with intravitreal dexamethasone implant. Observations: A 67 year-old man diagnosed with unresectable pancreatic cancer presented with decreased vision in both eyes while receiving nab-paclitaxel. He was diagnosed with CME and intravitreal dexamethasone implants were administered in both eyes. Central retinal thickness (CRT) of both eye decreased 1 month after the implant but CME persisted. 2 months after Ozurdex implant nabpaclitaxel was discontinued, improving central macular thickness and the CME significantly in both eyes. Conclusion and importance: Cessation of nab-paclitaxel could lead to resolution of CME more than intravitreal dexamethasone implant, although intravitreal dexamethasone implant achieved some reduction in central macular thickness.http://www.sciencedirect.com/science/article/pii/S2451993620300347Cystoid macular edemaPaclitaxelIntravitreal dexamethasone implant |
| spellingShingle | Barbara Burgos-Blasco Samuel Hernandez-Ruiz Lorenzo Lopez-Guajardo Juan Donate-Lopez Dexamethasone intravitreal implant in cystoid macular edema secondary to paclitaxel therapy American Journal of Ophthalmology Case Reports Cystoid macular edema Paclitaxel Intravitreal dexamethasone implant |
| title | Dexamethasone intravitreal implant in cystoid macular edema secondary to paclitaxel therapy |
| title_full | Dexamethasone intravitreal implant in cystoid macular edema secondary to paclitaxel therapy |
| title_fullStr | Dexamethasone intravitreal implant in cystoid macular edema secondary to paclitaxel therapy |
| title_full_unstemmed | Dexamethasone intravitreal implant in cystoid macular edema secondary to paclitaxel therapy |
| title_short | Dexamethasone intravitreal implant in cystoid macular edema secondary to paclitaxel therapy |
| title_sort | dexamethasone intravitreal implant in cystoid macular edema secondary to paclitaxel therapy |
| topic | Cystoid macular edema Paclitaxel Intravitreal dexamethasone implant |
| url | http://www.sciencedirect.com/science/article/pii/S2451993620300347 |
| work_keys_str_mv | AT barbaraburgosblasco dexamethasoneintravitrealimplantincystoidmacularedemasecondarytopaclitaxeltherapy AT samuelhernandezruiz dexamethasoneintravitrealimplantincystoidmacularedemasecondarytopaclitaxeltherapy AT lorenzolopezguajardo dexamethasoneintravitrealimplantincystoidmacularedemasecondarytopaclitaxeltherapy AT juandonatelopez dexamethasoneintravitrealimplantincystoidmacularedemasecondarytopaclitaxeltherapy |