A patient-designed tissue-engineered model of the infiltrative glioblastoma microenvironment
Abstract Glioblastoma is an aggressive brain cancer characterized by diffuse infiltration. Infiltrated glioma cells persist in the brain post-resection where they interact with glial cells and experience interstitial fluid flow. We use patient-derived glioma stem cells and human glial cells (i.e., a...
Main Authors: | , , , , , , , , , , , , , , |
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Format: | Article |
Language: | English |
Published: |
Nature Portfolio
2022-07-01
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Series: | npj Precision Oncology |
Online Access: | https://doi.org/10.1038/s41698-022-00290-8 |