A patient-designed tissue-engineered model of the infiltrative glioblastoma microenvironment

Abstract Glioblastoma is an aggressive brain cancer characterized by diffuse infiltration. Infiltrated glioma cells persist in the brain post-resection where they interact with glial cells and experience interstitial fluid flow. We use patient-derived glioma stem cells and human glial cells (i.e., a...

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Bibliographic Details
Main Authors: R. C. Cornelison, J. X. Yuan, K. M. Tate, A. Petrosky, G. F. Beeghly, M. Bloomfield, S. C. Schwager, A. L. Berr, C. A. Stine, D. Cimini, F. F. Bafakih, J. W. Mandell, B. W. Purow, B. J. Horton, J. M. Munson
Format: Article
Language:English
Published: Nature Portfolio 2022-07-01
Series:npj Precision Oncology
Online Access:https://doi.org/10.1038/s41698-022-00290-8