Structural modification may be a way to make isoquinoline alkaloids efficient antibacterial drugs

Structural modification may be a way to make isoquinoline alkaloids efficient antibacterial drugs

Isoquinoline alkaloids are a kind of small molecular compounds with isoquinoline structure which widely exist in natural plants. A large number of studies have confirmed that these substances have a variety of biological activities, such as antibacterial, anti-tumor, anti-hyperglycemia, anti-virus,...

Full description

Bibliographic Details
Main Authors:	Hui Wang, Yuanjing Zhao, Haoran Xu, Ping Wang, Simin Chen
Format:	Article
Language:	English
Published:	Elsevier 2023-11-01
Series:	Arabian Journal of Chemistry
Subjects:	Isoquinoline alkaloids Antibacterial activity Structural modification Synthesis method
Online Access:	http://www.sciencedirect.com/science/article/pii/S1878535223006664

Similar Items

Effect of magnetization on antibacterial, lipid-lowering and antioxidant activities of isoquinoline alkaloids
by: Xueting Feng, et al.
Published: (2025-01-01)

A Concise Total Synthesis of the Fungal Isoquinoline Alkaloid TMC-120B
by: Ahmad K. Haidar, et al.
Published: (2022-01-01)

Research Progress on Neuroprotective Effects of Isoquinoline Alkaloids
by: Jinhua Li, et al.
Published: (2023-06-01)

Protective effect of Macleaya cordata isoquinoline alkaloids on lipopolysaccharide-induced liver injury in broilers
by: Jiaxin Chen, et al.
Published: (2024-01-01)

Research Progress of Isoquinoline Alkaloids against Liver Cancer Based on Network Pharmacology and Literature
by: SUN Xing-qian, et al.
Published: (2021-01-01)

Transcriptome analysis reveals cadmium exposure enhanced the isoquinoline alkaloid biosynthesis and disease resistance in Coptis chinensis
by: Xin Li, et al.
Published: (2024-02-01)

Interaction of isoquinoline alkaloids with pyrimidine motif triplex DNA by mass spectrometry and spectroscopies reveals diverse mechanisms
by: Zhaoyang Xie, et al.
Published: (2023-04-01)

Inhibitory Activity of Quaternary Isoquinoline Alkaloids on Soluble Epoxide Hydrolase
by: Jang Hoon Kim, et al.
Published: (2022-09-01)

Effectiveness of Volatile Natural Deep Eutectic Solvents (VNADESs) for the Green Extraction of <i>Chelidonium majus</i> Isoquinoline Alkaloids
by: Maciej Strzemski, et al.
Published: (2022-04-01)

Effects of a dietary isoquinoline alkaloids blend on gut antioxidant capacity and gut barrier of young broilers
by: Vasileios Paraskeuas, et al.
Published: (2024-05-01)

Bioactivity and In Silico Studies of Isoquinoline and Related Alkaloids as Promising Antiviral Agents: An Insight
by: Divya Sharma, et al.
Published: (2022-12-01)

Transcriptome analysis reveals the potential mechanism of altering viability, yield, and isoquinoline alkaloids in Coptis chinensis through Cunninghamia lanceolata understory cultivation
by: Yuanyuan Duan, et al.
Published: (2024-02-01)

Isoquinoline alkaloids/
by: 343379 Shamma, Maurice
Published: (1972)

Hypecotumines A-D, new isoquinoline alkaloids with potential PCSK9 inhibition activity from Hypecoum erectum L.
by: Yinling Wei, et al.
Published: (2024-10-01)

Isoquinoline Alkaloids as Protein Tyrosine Phosphatase Inhibitors from a Deep-Sea-Derived Fungus <em>Aspergillus puniceus</em>
by: Cheng-Mei Liu, et al.
Published: (2022-01-01)

Can Isoquinoline Alkaloids Affect Platelet Aggregation in Whole Human Blood?
by: Mst Shamima Parvin, et al.
Published: (2022-07-01)

Biological Activities of Some Isoquinoline Alkaloids from <i>Fumaria schleicheri</i> Soy. Will.
by: Ramona Păltinean, et al.
Published: (2022-04-01)

Isoquinoline Alkaloid Contents in <i>Macleaya cordata</i> Extracts and Their Acetylcholinesterase and Butyrylcholinesterase Inhibition
by: Tomasz Tuzimski, et al.
Published: (2022-06-01)

Application of HPLC-DAD for In Vitro Investigation of Acetylcholinesterase Inhibition Activity of Selected Isoquinoline Alkaloids from <i>Sanguinaria canadensis</i> Extracts
by: Tomasz Tuzimski, et al.
Published: (2021-01-01)

Isolation of microorganisms capable of degrading isoquinoline under aerobic conditions /
by: 304503 Aislabie, Jackie, et al.

Cyclometalated iridium(III) complex based on isoquinoline alkaloid synergistically elicits the ICD response and IDO inhibition via autophagy-dependent ferroptosis
by: Yuan Lu, et al.
Published: (2025-01-01)

Determination of Cytotoxic Activity of Selected Isoquinoline Alkaloids and Plant Extracts Obtained from Various Parts of <i>Mahonia aquifolium</i> Collected in Various Vegetation Seasons
by: Tomasz Tuzimski, et al.
Published: (2021-02-01)

Natural isoquinoline alkaloids: Pharmacological features and multi-target potential for complex diseases
by: Erika Plazas, et al.
Published: (2022-03-01)

Recent Advances in the Synthesis of Isoquinoline-Fused Benzimidazoles
by: Dylan J. Twardy, et al.
Published: (2022-03-01)

Macleaya cordata isoquinoline alkaloids attenuate Escherichia coli lipopolysaccharide-induced intestinal epithelium injury in broiler chickens by co-regulating the TLR4/MyD88/NF-κB and Nrf2 signaling pathways
by: Yang Liu, et al.
Published: (2024-01-01)

Indolo‐pyrido‐isoquinolin based alkaloid inhibits growth, invasion and migration of breast cancer cells via activation of p53‐miR34a axis
by: Dimiter B. Avtanski, et al.
Published: (2016-08-01)

Ex Vivo and In Vivo Study of Some Isoquinoline Precursors
by: Miglena Milusheva, et al.
Published: (2022-06-01)

<i>Hypecoum</i> spp.—Chemistry and Biological Activity of Alkaloids
by: Nadezhda Kostova, et al.
Published: (2023-09-01)

Determination of Some Isoquinoline Alkaloids in Extracts Obtained from Selected Plants of the Ranunculaceae, Papaveraceae and Fumarioideae Families by Liquid Chromatography and In Vitro and In Vivo Investigations of Their Cytotoxic Activity
by: Justyna Misiurek, et al.
Published: (2023-04-01)

Large variability in the alkaloid content of Corydalis yanhusuo dietary supplements
by: Paula B. Luis, et al.
Published: (2025-01-01)

Expatiating the Pharmacological and Nanotechnological Aspects of the Alkaloidal Drug Berberine: Current and Future Trends
by: Tapan Behl, et al.
Published: (2022-06-01)

Synthesis and Anti-HIV Activity of a Novel Series of Isoquinoline-Based CXCR4 Antagonists
by: Mastaneh Safarnejad Shad, et al.
Published: (2021-10-01)

Interactions of Isoquinoline Alkaloids with Transition Metals Iron and Copper
by: Mst Shamima Parvin, et al.
Published: (2022-09-01)

Alkaloids of <i>Dicranostigma franchetianum</i> (Papaveraceae) and Berberine Derivatives as a New Class of Antimycobacterial Agents
by: Viriyanata Wijaya, et al.
Published: (2022-06-01)

Phellodendronoside A Exerts Anticancer Effects Depending on Inducing Apoptosis Through ROS/Nrf2/Notch Pathway and Modulating Metabolite Profiles in Hepatocellular Carcinoma
by: Si Y, et al.
Published: (2023-06-01)

Anti-Alphaviral Alkaloids: Focus on Some Isoquinolines, Indoles and Quinolizidines
by: Anne-Laure Sandenon Seteyen, et al.
Published: (2022-08-01)

Screening an In-House Isoquinoline Alkaloids Library for New Blockers of Voltage-Gated Na<sup>+</sup> Channels Using Voltage Sensor Fluorescent Probes: Hits and Biases
by: Quentin Coquerel, et al.
Published: (2022-06-01)

Endophytic Bacteria Producing Alkaloid as Antibacterial and Antioxidant Agent from Hibiscus tiliaceus Leaves
by: Purbowatiningrum Ria Sarjono, et al.
Published: (2024-04-01)

Research Progress on Antibacterial Activities and Mechanisms of Natural Alkaloids: A Review
by: Yumei Yan, et al.
Published: (2021-03-01)

Insecticidal Activity of Extracts, Fractions, and Pure Molecules of <i>Cissampelos pareira</i> Linnaeus against Aphid, <i>Aphis craccivora</i> Koch
by: Surekha Kumari, et al.
Published: (2022-01-01)