Di-tert-butyl N-[2,6-bis(methoxymethoxy)phenyl]iminodiacetate
The title molecule, C20H31NO8, has pseudo-C2 symmetry about the C—N bond, with the bis(tert-butoxycarbonyl)amino group twisted from the benzene ring plane by ca 60° and the bulky tert-butoxycarbonyl (Boc) groups are orientated away from the substituted aniline group. As pa...
Main Authors: | , , , , |
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Format: | Article |
Language: | English |
Published: |
International Union of Crystallography
2009-04-01
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Series: | Acta Crystallographica Section E |
Online Access: | http://scripts.iucr.org/cgi-bin/paper?S1600536809009246 |
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author | Ben Capuano Ian T. Crosby Craig M. Forsyth Yelena Khakham David T. Manallack |
author_facet | Ben Capuano Ian T. Crosby Craig M. Forsyth Yelena Khakham David T. Manallack |
author_sort | Ben Capuano |
collection | DOAJ |
description | The title molecule, C20H31NO8, has pseudo-C2 symmetry about the C—N bond, with the bis(tert-butoxycarbonyl)amino group twisted from the benzene ring plane by ca 60° and the bulky tert-butoxycarbonyl (Boc) groups are orientated away from the substituted aniline group. As part of an antibacterial drug discovery programme furnishing analogues of platensimycin, we unexpectedly synthesized the bis-Boc-protected aniline. |
first_indexed | 2024-12-20T22:12:08Z |
format | Article |
id | doaj.art-42c70d98083c4779b73f999116c30525 |
institution | Directory Open Access Journal |
issn | 1600-5368 |
language | English |
last_indexed | 2024-12-20T22:12:08Z |
publishDate | 2009-04-01 |
publisher | International Union of Crystallography |
record_format | Article |
series | Acta Crystallographica Section E |
spelling | doaj.art-42c70d98083c4779b73f999116c305252022-12-21T19:25:09ZengInternational Union of CrystallographyActa Crystallographica Section E1600-53682009-04-01654o819o81910.1107/S1600536809009246Di-tert-butyl N-[2,6-bis(methoxymethoxy)phenyl]iminodiacetateBen CapuanoIan T. CrosbyCraig M. ForsythYelena KhakhamDavid T. ManallackThe title molecule, C20H31NO8, has pseudo-C2 symmetry about the C—N bond, with the bis(tert-butoxycarbonyl)amino group twisted from the benzene ring plane by ca 60° and the bulky tert-butoxycarbonyl (Boc) groups are orientated away from the substituted aniline group. As part of an antibacterial drug discovery programme furnishing analogues of platensimycin, we unexpectedly synthesized the bis-Boc-protected aniline.http://scripts.iucr.org/cgi-bin/paper?S1600536809009246 |
spellingShingle | Ben Capuano Ian T. Crosby Craig M. Forsyth Yelena Khakham David T. Manallack Di-tert-butyl N-[2,6-bis(methoxymethoxy)phenyl]iminodiacetate Acta Crystallographica Section E |
title | Di-tert-butyl N-[2,6-bis(methoxymethoxy)phenyl]iminodiacetate |
title_full | Di-tert-butyl N-[2,6-bis(methoxymethoxy)phenyl]iminodiacetate |
title_fullStr | Di-tert-butyl N-[2,6-bis(methoxymethoxy)phenyl]iminodiacetate |
title_full_unstemmed | Di-tert-butyl N-[2,6-bis(methoxymethoxy)phenyl]iminodiacetate |
title_short | Di-tert-butyl N-[2,6-bis(methoxymethoxy)phenyl]iminodiacetate |
title_sort | di tert butyl n 2 6 bis methoxymethoxy phenyl iminodiacetate |
url | http://scripts.iucr.org/cgi-bin/paper?S1600536809009246 |
work_keys_str_mv | AT bencapuano ditertbutyln26bismethoxymethoxyphenyliminodiacetate AT iantcrosby ditertbutyln26bismethoxymethoxyphenyliminodiacetate AT craigmforsyth ditertbutyln26bismethoxymethoxyphenyliminodiacetate AT yelenakhakham ditertbutyln26bismethoxymethoxyphenyliminodiacetate AT davidtmanallack ditertbutyln26bismethoxymethoxyphenyliminodiacetate |