Water absorption by decellularized dermis
Water absorption by decellularized dermis was investigated and compared with biopolymer and synthetic polymer hydrogels (glutaraldehyde-crosslinked gelatin and crosslinked poly(acrylamide) hydrogel, respectively). Porcine dermis was decellularized in an aqueous sodium dodecyl sulfate (SDS) solution....
| Main Authors: | , , , , , , , |
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| Format: | Article |
| Language: | English |
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Elsevier
2018-04-01
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| Series: | Heliyon |
| Subjects: | |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S2405844017326993 |
| _version_ | 1818516234884349952 |
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| author | Yongwei Zhang Takuya Iwata Kwangwoo Nam Tsuyoshi Kimura Pingli Wu Naoko Nakamura Yoshihide Hashimoto Akio Kishida |
| author_facet | Yongwei Zhang Takuya Iwata Kwangwoo Nam Tsuyoshi Kimura Pingli Wu Naoko Nakamura Yoshihide Hashimoto Akio Kishida |
| author_sort | Yongwei Zhang |
| collection | DOAJ |
| description | Water absorption by decellularized dermis was investigated and compared with biopolymer and synthetic polymer hydrogels (glutaraldehyde-crosslinked gelatin and crosslinked poly(acrylamide) hydrogel, respectively). Porcine dermis was decellularized in an aqueous sodium dodecyl sulfate (SDS) solution. Histological evaluation revealed that the SDS-treated dermis has much larger gaps between collagen fibrils than non-treated dermis, and that water absorption depends on these gaps. Decellularized dermis has low water absorptivity and the absorption obeys Fick's second law. During absorption, the water diffusion rate decreases with time and occurs in two steps. The first is rapid absorption into the large gaps, followed by slow absorption by the collagen fiber layer. Because of the gaps, decellularized dermis can absorb more water than native dermis and shows different water absorption behavior to glutaraldehyde-crosslinked gelatin and crosslinked poly(acrylamide) hydrogels. |
| first_indexed | 2024-12-11T00:39:22Z |
| format | Article |
| id | doaj.art-42d34ded152e436bb94d6acd5bea6613 |
| institution | Directory Open Access Journal |
| issn | 2405-8440 |
| language | English |
| last_indexed | 2024-12-11T00:39:22Z |
| publishDate | 2018-04-01 |
| publisher | Elsevier |
| record_format | Article |
| series | Heliyon |
| spelling | doaj.art-42d34ded152e436bb94d6acd5bea66132022-12-22T01:26:59ZengElsevierHeliyon2405-84402018-04-0144e00600Water absorption by decellularized dermisYongwei Zhang0Takuya Iwata1Kwangwoo Nam2Tsuyoshi Kimura3Pingli Wu4Naoko Nakamura5Yoshihide Hashimoto6Akio Kishida7Department of Material-based Medical Engineering, Institute of Biomaterials and Bioengineering, Tokyo Medical and Dental University, 2-3-10 Kanda-Surugadai, Chiyoda-ku, Tokyo 101-0062, JapanDepartment of Material-based Medical Engineering, Institute of Biomaterials and Bioengineering, Tokyo Medical and Dental University, 2-3-10 Kanda-Surugadai, Chiyoda-ku, Tokyo 101-0062, JapanDepartment of Material-based Medical Engineering, Institute of Biomaterials and Bioengineering, Tokyo Medical and Dental University, 2-3-10 Kanda-Surugadai, Chiyoda-ku, Tokyo 101-0062, JapanDepartment of Material-based Medical Engineering, Institute of Biomaterials and Bioengineering, Tokyo Medical and Dental University, 2-3-10 Kanda-Surugadai, Chiyoda-ku, Tokyo 101-0062, JapanDepartment of Material-based Medical Engineering, Institute of Biomaterials and Bioengineering, Tokyo Medical and Dental University, 2-3-10 Kanda-Surugadai, Chiyoda-ku, Tokyo 101-0062, JapanDepartment of Material-based Medical Engineering, Institute of Biomaterials and Bioengineering, Tokyo Medical and Dental University, 2-3-10 Kanda-Surugadai, Chiyoda-ku, Tokyo 101-0062, JapanDepartment of Material-based Medical Engineering, Institute of Biomaterials and Bioengineering, Tokyo Medical and Dental University, 2-3-10 Kanda-Surugadai, Chiyoda-ku, Tokyo 101-0062, JapanCorresponding author.; Department of Material-based Medical Engineering, Institute of Biomaterials and Bioengineering, Tokyo Medical and Dental University, 2-3-10 Kanda-Surugadai, Chiyoda-ku, Tokyo 101-0062, JapanWater absorption by decellularized dermis was investigated and compared with biopolymer and synthetic polymer hydrogels (glutaraldehyde-crosslinked gelatin and crosslinked poly(acrylamide) hydrogel, respectively). Porcine dermis was decellularized in an aqueous sodium dodecyl sulfate (SDS) solution. Histological evaluation revealed that the SDS-treated dermis has much larger gaps between collagen fibrils than non-treated dermis, and that water absorption depends on these gaps. Decellularized dermis has low water absorptivity and the absorption obeys Fick's second law. During absorption, the water diffusion rate decreases with time and occurs in two steps. The first is rapid absorption into the large gaps, followed by slow absorption by the collagen fiber layer. Because of the gaps, decellularized dermis can absorb more water than native dermis and shows different water absorption behavior to glutaraldehyde-crosslinked gelatin and crosslinked poly(acrylamide) hydrogels.http://www.sciencedirect.com/science/article/pii/S2405844017326993BioengineeringMaterials science |
| spellingShingle | Yongwei Zhang Takuya Iwata Kwangwoo Nam Tsuyoshi Kimura Pingli Wu Naoko Nakamura Yoshihide Hashimoto Akio Kishida Water absorption by decellularized dermis Heliyon Bioengineering Materials science |
| title | Water absorption by decellularized dermis |
| title_full | Water absorption by decellularized dermis |
| title_fullStr | Water absorption by decellularized dermis |
| title_full_unstemmed | Water absorption by decellularized dermis |
| title_short | Water absorption by decellularized dermis |
| title_sort | water absorption by decellularized dermis |
| topic | Bioengineering Materials science |
| url | http://www.sciencedirect.com/science/article/pii/S2405844017326993 |
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