Decoding the Heterogeneity of Malignant Gliomas by PET and MRI for Spatial Habitat Analysis of Hypoxia, Perfusion, and Diffusion Imaging: A Preliminary Study

Decoding the Heterogeneity of Malignant Gliomas by PET and MRI for Spatial Habitat Analysis of Hypoxia, Perfusion, and Diffusion Imaging: A Preliminary Study

BackgroundTumor heterogeneity poses major clinical challenges in high-grade gliomas (HGGs). Quantitative radiomic analysis with spatial tumor habitat clustering represents an innovative, non-invasive approach to represent and quantify tumor microenvironment heterogeneity. To date, habitat imaging ha...

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Bibliographic Details
Main Authors: Michele Bailo, Nicolò Pecco, Marcella Callea, Paola Scifo, Filippo Gagliardi, Luca Presotto, Valentino Bettinardi, Federico Fallanca, Paola Mapelli, Luigi Gianolli, Claudio Doglioni, Nicoletta Anzalone, Maria Picchio, Pietro Mortini, Andrea Falini, Antonella Castellano
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-07-01
Series:Frontiers in Neuroscience
Subjects:
high-grade glioma
PET
MRI
habitats
hypoxia imaging
perfusion-weighted imaging
Online Access:https://www.frontiersin.org/articles/10.3389/fnins.2022.885291/full

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