Different Geometry Design Structures of Tissue Scaffolds for Additive Manufacturing
The design and manufacturing cubic porous scaffolds are a considerable notion in tissue engineering (TE). From Additive manufacturing (AM) perspective, it has attained high appeal in the string of TE during the past decade. In the view of TE, the feasibility of manufacturing intricate porous scaffol...
| Main Authors: | , , , , |
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| Format: | Article |
| Language: | English |
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Islamic Azad University-Isfahan (Khorasgan) Branch
2021-12-01
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| Series: | International Journal of Advanced Design and Manufacturing Technology |
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| Online Access: | https://admt.isfahan.iau.ir/article_687307_4bf13e07014794d294bad3e959db9398.pdf |
| _version_ | 1797657315903537152 |
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| author | amirhossein Ehsani sadegh rahmati Mohammad Nikkhoo Shahram Etemadi Haghighi Mohammad Haghpanahi |
| author_facet | amirhossein Ehsani sadegh rahmati Mohammad Nikkhoo Shahram Etemadi Haghighi Mohammad Haghpanahi |
| author_sort | amirhossein Ehsani |
| collection | DOAJ |
| description | The design and manufacturing cubic porous scaffolds are a considerable notion in tissue engineering (TE). From Additive manufacturing (AM) perspective, it has attained high appeal in the string of TE during the past decade. In the view of TE, the feasibility of manufacturing intricate porous scaffolds with high accuracy contrast to prominent producing methods has caused AM the outstanding option for manufacturing scaffold. From design perspective, porous scaffold structures play a crucial task in TE as scaffold design with an adequate geometries provide a route to required strength and porosity. The target of this paper is achieve of best geometry to become an optimum mechanical strength and porosity of TE scaffolds. Hence, the cubic geometry has been chosen for scaffold and Cube, Cylinder and Hexagonal prism geometries have been selected for pore of structures. In addition, for noticing the porosity effects, pore size has been chosen in three size, and a whole of nine scaffolds have been designed. Designed scaffolds were generated using Fused Deposition Modeling (FDM) 3D Printer and dimensional specifications of scaffolds were evaluated by comparing the designed scaffolds with Scanning Electron Microscope (SEM). The samples were subjected to mechanical compression test and the results were verified with the Finite Element Analysis (FEA). The results showed that firstly, as the porosity increases, the compressive strength and modulus of elasticity obviously decreased in all geometry pore scaffolds. Secondly, as the geometry changes in similar porosity, cubic pore scaffold achieved higher compressive strength and modulus of elasticity than cylinder and hexagonal prime. Experimental and FEM validated results proposed a privileged feasible pore geometry of cubic scaffold to be used in design and manufacturing of TE scaffolds. |
| first_indexed | 2024-03-11T17:42:43Z |
| format | Article |
| id | doaj.art-42d7d985833546979e23abc3d0febaeb |
| institution | Directory Open Access Journal |
| issn | 2252-0406 2383-4447 |
| language | English |
| last_indexed | 2024-03-11T17:42:43Z |
| publishDate | 2021-12-01 |
| publisher | Islamic Azad University-Isfahan (Khorasgan) Branch |
| record_format | Article |
| series | International Journal of Advanced Design and Manufacturing Technology |
| spelling | doaj.art-42d7d985833546979e23abc3d0febaeb2023-10-18T08:47:01ZengIslamic Azad University-Isfahan (Khorasgan) BranchInternational Journal of Advanced Design and Manufacturing Technology2252-04062383-44472021-12-011449110410.30495/admt.2021.1936526.1298687307Different Geometry Design Structures of Tissue Scaffolds for Additive Manufacturingamirhossein Ehsani0sadegh rahmati1Mohammad Nikkhoo2Shahram Etemadi Haghighi3Mohammad Haghpanahi4Department of Mechanical Engineering, Science and Research Branch, Islamic Azad University, Tehran, IranDepartment of Biomedical Engineering, Science and Research Branch, Islamic Azad University, Tehran, IranDepartment of Biomedical Engineering, Science and Research Branch, Islamic Azad University, Tehran, IranDepartment of Mechanical Engineering, Science and Research Branch, Islamic Azad University, Tehran, IranBiomechanics Group, Department of Mechanical Engineering, Iran University of Science and Technology, Tehran, IranThe design and manufacturing cubic porous scaffolds are a considerable notion in tissue engineering (TE). From Additive manufacturing (AM) perspective, it has attained high appeal in the string of TE during the past decade. In the view of TE, the feasibility of manufacturing intricate porous scaffolds with high accuracy contrast to prominent producing methods has caused AM the outstanding option for manufacturing scaffold. From design perspective, porous scaffold structures play a crucial task in TE as scaffold design with an adequate geometries provide a route to required strength and porosity. The target of this paper is achieve of best geometry to become an optimum mechanical strength and porosity of TE scaffolds. Hence, the cubic geometry has been chosen for scaffold and Cube, Cylinder and Hexagonal prism geometries have been selected for pore of structures. In addition, for noticing the porosity effects, pore size has been chosen in three size, and a whole of nine scaffolds have been designed. Designed scaffolds were generated using Fused Deposition Modeling (FDM) 3D Printer and dimensional specifications of scaffolds were evaluated by comparing the designed scaffolds with Scanning Electron Microscope (SEM). The samples were subjected to mechanical compression test and the results were verified with the Finite Element Analysis (FEA). The results showed that firstly, as the porosity increases, the compressive strength and modulus of elasticity obviously decreased in all geometry pore scaffolds. Secondly, as the geometry changes in similar porosity, cubic pore scaffold achieved higher compressive strength and modulus of elasticity than cylinder and hexagonal prime. Experimental and FEM validated results proposed a privileged feasible pore geometry of cubic scaffold to be used in design and manufacturing of TE scaffolds.https://admt.isfahan.iau.ir/article_687307_4bf13e07014794d294bad3e959db9398.pdfcubic scaffoldpore geometrytissue engineeringadditive manufacturingmechanical strengthfinite element analysis |
| spellingShingle | amirhossein Ehsani sadegh rahmati Mohammad Nikkhoo Shahram Etemadi Haghighi Mohammad Haghpanahi Different Geometry Design Structures of Tissue Scaffolds for Additive Manufacturing International Journal of Advanced Design and Manufacturing Technology cubic scaffold pore geometry tissue engineering additive manufacturing mechanical strength finite element analysis |
| title | Different Geometry Design Structures of Tissue Scaffolds for Additive Manufacturing |
| title_full | Different Geometry Design Structures of Tissue Scaffolds for Additive Manufacturing |
| title_fullStr | Different Geometry Design Structures of Tissue Scaffolds for Additive Manufacturing |
| title_full_unstemmed | Different Geometry Design Structures of Tissue Scaffolds for Additive Manufacturing |
| title_short | Different Geometry Design Structures of Tissue Scaffolds for Additive Manufacturing |
| title_sort | different geometry design structures of tissue scaffolds for additive manufacturing |
| topic | cubic scaffold pore geometry tissue engineering additive manufacturing mechanical strength finite element analysis |
| url | https://admt.isfahan.iau.ir/article_687307_4bf13e07014794d294bad3e959db9398.pdf |
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