Peculiarities of immune reaction in patients with drug-resistant pulmonary tuberculosis

The results of research the cytokine-secretion activity of mononuclear leukocytes, apoptosis and proliferation of lymphocytes for patients with infiltrative pulmonary tuberculosis has been presented in this article. It has been showed that patients with drug-resistant pulmonary tuberculosis had more...

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Main Authors: T. Ye. Kononova, O. I. Urazova, V. V. Novitsky, Ye. G. Churina, M. V. Ignatov
Format: Article
Language:English
Published: Siberian State Medical University (Tomsk) 2012-08-01
Series:Бюллетень сибирской медицины
Subjects:
Online Access:https://bulletin.ssmu.ru/jour/article/view/566
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author T. Ye. Kononova
O. I. Urazova
V. V. Novitsky
Ye. G. Churina
M. V. Ignatov
author_facet T. Ye. Kononova
O. I. Urazova
V. V. Novitsky
Ye. G. Churina
M. V. Ignatov
author_sort T. Ye. Kononova
collection DOAJ
description The results of research the cytokine-secretion activity of mononuclear leukocytes, apoptosis and proliferation of lymphocytes for patients with infiltrative pulmonary tuberculosis has been presented in this article. It has been showed that patients with drug-resistant pulmonary tuberculosis had more evident of damages, particularly significant depression of proliferation of lymphocytes, decreased number of cells expressing CD95-receptor as well as disturbance the secretion of immunoregulatory cytokines.
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spelling doaj.art-42dbca8c10804f958de3e01e1f2307952023-03-13T09:58:17ZengSiberian State Medical University (Tomsk)Бюллетень сибирской медицины1682-03631819-36842012-08-0111416016210.20538/1682-0363-2012-4-160-162518Peculiarities of immune reaction in patients with drug-resistant pulmonary tuberculosisT. Ye. Kononova0O. I. Urazova1V. V. Novitsky2Ye. G. Churina3M. V. Ignatov4Сибирский государственный медицинский университет, г. ТомскСибирский государственный медицинский университет, г. ТомскСибирский государственный медицинский университет, г. ТомскСибирский государственный медицинский университет, г. ТомскСибирский государственный медицинский университет, г. ТомскThe results of research the cytokine-secretion activity of mononuclear leukocytes, apoptosis and proliferation of lymphocytes for patients with infiltrative pulmonary tuberculosis has been presented in this article. It has been showed that patients with drug-resistant pulmonary tuberculosis had more evident of damages, particularly significant depression of proliferation of lymphocytes, decreased number of cells expressing CD95-receptor as well as disturbance the secretion of immunoregulatory cytokines.https://bulletin.ssmu.ru/jour/article/view/566лекарственно-устойчивый туберкулез легкихцитокиныпролиферацияапоптоз лимфоцитов
spellingShingle T. Ye. Kononova
O. I. Urazova
V. V. Novitsky
Ye. G. Churina
M. V. Ignatov
Peculiarities of immune reaction in patients with drug-resistant pulmonary tuberculosis
Бюллетень сибирской медицины
лекарственно-устойчивый туберкулез легких
цитокины
пролиферация
апоптоз лимфоцитов
title Peculiarities of immune reaction in patients with drug-resistant pulmonary tuberculosis
title_full Peculiarities of immune reaction in patients with drug-resistant pulmonary tuberculosis
title_fullStr Peculiarities of immune reaction in patients with drug-resistant pulmonary tuberculosis
title_full_unstemmed Peculiarities of immune reaction in patients with drug-resistant pulmonary tuberculosis
title_short Peculiarities of immune reaction in patients with drug-resistant pulmonary tuberculosis
title_sort peculiarities of immune reaction in patients with drug resistant pulmonary tuberculosis
topic лекарственно-устойчивый туберкулез легких
цитокины
пролиферация
апоптоз лимфоцитов
url https://bulletin.ssmu.ru/jour/article/view/566
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AT vvnovitsky peculiaritiesofimmunereactioninpatientswithdrugresistantpulmonarytuberculosis
AT yegchurina peculiaritiesofimmunereactioninpatientswithdrugresistantpulmonarytuberculosis
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