Understanding DNA Damage Response and DNA Repair in Multiple Myeloma

Understanding DNA Damage Response and DNA Repair in Multiple Myeloma

Multiple myeloma (MM) is a plasma cell malignancy characterized by several genetic abnormalities, including chromosomal translocations, genomic deletions and gains, and point mutations. DNA damage response (DDR) and DNA repair mechanisms are altered in MM to allow for tumor development, progression,...

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Bibliographic Details
Main Authors: Cole Petrilla, Joshua Galloway, Ruchi Kudalkar, Aya Ismael, Francesca Cottini
Format: Article
Language:English
Published: MDPI AG 2023-08-01
Series:Cancers
Subjects:
multiple myeloma
DNA damage response
DNA repair
Online Access:https://www.mdpi.com/2072-6694/15/16/4155

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