Targeting 7KCh-Induced Cell Death Response Mediated by p38, P2X7 and GSDME in Retinal Pigment Epithelium Cells with Sterculic Acid

Targeting 7KCh-Induced Cell Death Response Mediated by p38, P2X7 and GSDME in Retinal Pigment Epithelium Cells with Sterculic Acid

Age-related macular degeneration (AMD) is the main cause of blindness in developed countries. AMD is characterized by the formation of drusen, which are lipidic deposits, between retinal pigment epithelium (RPE) and the choroid. One of the main molecules accumulated in drusen is 7-Ketocholesterol (7...

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Bibliographic Details
Main Authors:	Ana Pariente, Rafael Peláez, Rodrigo Ochoa, Álvaro Pérez-Sala, Ángela Villanueva-Martínez, Miriam Bobadilla, Ignacio M. Larráyoz
Format:	Article
Language:	English
Published:	MDPI AG 2023-11-01
Series:	Pharmaceutics
Subjects:	7-ketocholesterol sterculic acid AMD retina cell death P2X7
Online Access:	https://www.mdpi.com/1999-4923/15/11/2590

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