Intrathecal morphine delivery at prepontine cistern to control refractory cancer-related pain: a case report of extensive metastatic and refractory cancer pain
Abstract Background Extensive metastatic and refractory cancer pain is common, and exhibits a dissatisfactory response to the conventional intrathecal infusion of opioid analgesics. Case Presentation The present study reports a case of an extensive metastatic esophageal cancer patient with severe in...
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| Format: | Article |
| Language: | English |
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BMC
2024-02-01
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| Series: | BMC Anesthesiology |
| Subjects: | |
| Online Access: | https://doi.org/10.1186/s12871-024-02426-8 |
| _version_ | 1797273456021078016 |
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| author | Qing Li Yan-ling Long Yun-wu He Hui Long Zhen-ping Xiao Yong-lin Li Wu-zhou Yang Li-ping Jiang Wei Gao Cong Zou |
| author_facet | Qing Li Yan-ling Long Yun-wu He Hui Long Zhen-ping Xiao Yong-lin Li Wu-zhou Yang Li-ping Jiang Wei Gao Cong Zou |
| author_sort | Qing Li |
| collection | DOAJ |
| description | Abstract Background Extensive metastatic and refractory cancer pain is common, and exhibits a dissatisfactory response to the conventional intrathecal infusion of opioid analgesics. Case Presentation The present study reports a case of an extensive metastatic esophageal cancer patient with severe intractable pain, who underwent translumbar subarachnoid puncture with intrathecal catheterization to the prepontine cistern. After continuous infusion of low-dose morphine, the pain was well-controlled with a decrease in the numeric rating scale (NRS) of pain score from 9 to 0, and the few adverse reactions to the treatment disappeared at a low dose of morphine. Conclusions The patient achieved a good quality of life during the one-month follow-up period. |
| first_indexed | 2024-03-07T14:44:31Z |
| format | Article |
| id | doaj.art-42e0aa43134d48be9aafc73175dd74c4 |
| institution | Directory Open Access Journal |
| issn | 1471-2253 |
| language | English |
| last_indexed | 2024-03-07T14:44:31Z |
| publishDate | 2024-02-01 |
| publisher | BMC |
| record_format | Article |
| series | BMC Anesthesiology |
| spelling | doaj.art-42e0aa43134d48be9aafc73175dd74c42024-03-05T20:05:01ZengBMCBMC Anesthesiology1471-22532024-02-012411510.1186/s12871-024-02426-8Intrathecal morphine delivery at prepontine cistern to control refractory cancer-related pain: a case report of extensive metastatic and refractory cancer painQing Li0Yan-ling Long1Yun-wu He2Hui Long3Zhen-ping Xiao4Yong-lin Li5Wu-zhou Yang6Li-ping Jiang7Wei Gao8Cong Zou9Department of Pain and Rehabilitation, The Second Affiliated Hospital, University of South ChinaDepartment of Pain and Rehabilitation, The Second Affiliated Hospital, University of South ChinaDepartment of Pain and Rehabilitation, The Second Affiliated Hospital, University of South ChinaDepartment of Pain and Rehabilitation, The Second Affiliated Hospital, University of South ChinaDepartment of Pain and Rehabilitation, The Second Affiliated Hospital, University of South ChinaDepartment of Pain and Rehabilitation, The Second Affiliated Hospital, University of South ChinaDepartment of Pain and Rehabilitation, The Second Affiliated Hospital, University of South ChinaDepartment of Pain and Rehabilitation, The Second Affiliated Hospital, University of South ChinaDepartment of Pain and Rehabilitation, The Second Affiliated Hospital, University of South ChinaDepartment of Pain and Rehabilitation, The Second Affiliated Hospital, University of South ChinaAbstract Background Extensive metastatic and refractory cancer pain is common, and exhibits a dissatisfactory response to the conventional intrathecal infusion of opioid analgesics. Case Presentation The present study reports a case of an extensive metastatic esophageal cancer patient with severe intractable pain, who underwent translumbar subarachnoid puncture with intrathecal catheterization to the prepontine cistern. After continuous infusion of low-dose morphine, the pain was well-controlled with a decrease in the numeric rating scale (NRS) of pain score from 9 to 0, and the few adverse reactions to the treatment disappeared at a low dose of morphine. Conclusions The patient achieved a good quality of life during the one-month follow-up period.https://doi.org/10.1186/s12871-024-02426-8Extensive metastatic and refractory cancer painPrepontine cisternIntrathecal deliverySubarachnoidOpioid receptorsNumeric rating scale (NRS) |
| spellingShingle | Qing Li Yan-ling Long Yun-wu He Hui Long Zhen-ping Xiao Yong-lin Li Wu-zhou Yang Li-ping Jiang Wei Gao Cong Zou Intrathecal morphine delivery at prepontine cistern to control refractory cancer-related pain: a case report of extensive metastatic and refractory cancer pain BMC Anesthesiology Extensive metastatic and refractory cancer pain Prepontine cistern Intrathecal delivery Subarachnoid Opioid receptors Numeric rating scale (NRS) |
| title | Intrathecal morphine delivery at prepontine cistern to control refractory cancer-related pain: a case report of extensive metastatic and refractory cancer pain |
| title_full | Intrathecal morphine delivery at prepontine cistern to control refractory cancer-related pain: a case report of extensive metastatic and refractory cancer pain |
| title_fullStr | Intrathecal morphine delivery at prepontine cistern to control refractory cancer-related pain: a case report of extensive metastatic and refractory cancer pain |
| title_full_unstemmed | Intrathecal morphine delivery at prepontine cistern to control refractory cancer-related pain: a case report of extensive metastatic and refractory cancer pain |
| title_short | Intrathecal morphine delivery at prepontine cistern to control refractory cancer-related pain: a case report of extensive metastatic and refractory cancer pain |
| title_sort | intrathecal morphine delivery at prepontine cistern to control refractory cancer related pain a case report of extensive metastatic and refractory cancer pain |
| topic | Extensive metastatic and refractory cancer pain Prepontine cistern Intrathecal delivery Subarachnoid Opioid receptors Numeric rating scale (NRS) |
| url | https://doi.org/10.1186/s12871-024-02426-8 |
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