Functional Evaluation of Major Salivary Glands Using Viscosity PLUS and 2D Shear-Wave PLUS Elastography Techniques in Healthy Subjects—A Pilot Study
Biological soft tissues are characterized by viscoelastic properties. The propagation of shear waves within tissues is influenced by both elasticity, which is linked to the shear wave speed, and viscosity, which is linked to the shear wave dispersion. This study aimed to functionally assess the paro...
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| Format: | Article |
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MDPI AG
2022-08-01
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| Series: | Diagnostics |
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| Online Access: | https://www.mdpi.com/2075-4418/12/8/1963 |
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| author | Delia Doris Muntean Manuela Lavinia Lenghel Diana-Raluca Petea-Balea Anca Ileana Ciurea Carolina Solomon Sorin Marian Dudea |
| author_facet | Delia Doris Muntean Manuela Lavinia Lenghel Diana-Raluca Petea-Balea Anca Ileana Ciurea Carolina Solomon Sorin Marian Dudea |
| author_sort | Delia Doris Muntean |
| collection | DOAJ |
| description | Biological soft tissues are characterized by viscoelastic properties. The propagation of shear waves within tissues is influenced by both elasticity, which is linked to the shear wave speed, and viscosity, which is linked to the shear wave dispersion. This study aimed to functionally assess the parotid glands (PG) and submandibular glands (SMG) in a group of 40 healthy subjects using the novel Viscosity PLUS (Vi.PLUS) and 2D Shear-Wave Elastography PLUS (2D-SWE.PLUS) techniques. The viscosity and stiffness of PG and SMG were measured before and after gustatory stimulation with a sialagogue agent (commercially available lemon juice) using the new SuperSonic MACH 30 ultrasound system equipped with a curvilinear C6-1X transducer. PG presented a mean basal viscosity and elasticity of 2.10 ± 0.19 Pa.s and 11.32 ± 1.91 kPa, respectively, which significantly increased poststimulation to 2.39 ± 0.17 Pa.s (<i>p</i> < 0.001) and 12.58 ± 1.92 kPa (<i>p</i> < 0.001), respectively. SMG did not present statistically increased values of viscosity and elasticity following stimulation (2.31 ± 015 Pa.s vs. 2.37 ± 0.18 Pa.s, <i>p</i> = 0.086, and 10.40 ± 1.64 kPa vs. 10.90 ± 1.98 kPa, <i>p</i> = 0.074, respectively). Vi.PLUS measurements presented a good positive correlation with 2D-SWE.PLUS values for PG and SMG, before and after stimulation. Gender and BMI were not confounding factors for these two parameters. Vi.PLUS represents an innovative non-invasive imaging technique that, together with 2D-SWE.PLUS proves to be useful in functionally assessing the major salivary glands in healthy subjects. |
| first_indexed | 2024-03-09T09:58:11Z |
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| id | doaj.art-42e12477dea3444abcdba95aefe2a66c |
| institution | Directory Open Access Journal |
| issn | 2075-4418 |
| language | English |
| last_indexed | 2024-03-09T09:58:11Z |
| publishDate | 2022-08-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Diagnostics |
| spelling | doaj.art-42e12477dea3444abcdba95aefe2a66c2023-12-01T23:36:38ZengMDPI AGDiagnostics2075-44182022-08-01128196310.3390/diagnostics12081963Functional Evaluation of Major Salivary Glands Using Viscosity PLUS and 2D Shear-Wave PLUS Elastography Techniques in Healthy Subjects—A Pilot StudyDelia Doris Muntean0Manuela Lavinia Lenghel1Diana-Raluca Petea-Balea2Anca Ileana Ciurea3Carolina Solomon4Sorin Marian Dudea5Department of Radiology, “Iuliu Hațieganu” University of Medicine and Pharmacy, 400012 Cluj-Napoca, RomaniaDepartment of Radiology, “Iuliu Hațieganu” University of Medicine and Pharmacy, 400012 Cluj-Napoca, RomaniaDepartment of Radiology, “Iuliu Hațieganu” University of Medicine and Pharmacy, 400012 Cluj-Napoca, RomaniaDepartment of Radiology, “Iuliu Hațieganu” University of Medicine and Pharmacy, 400012 Cluj-Napoca, RomaniaDepartment of Radiology, “Iuliu Hațieganu” University of Medicine and Pharmacy, 400012 Cluj-Napoca, RomaniaDepartment of Radiology, “Iuliu Hațieganu” University of Medicine and Pharmacy, 400012 Cluj-Napoca, RomaniaBiological soft tissues are characterized by viscoelastic properties. The propagation of shear waves within tissues is influenced by both elasticity, which is linked to the shear wave speed, and viscosity, which is linked to the shear wave dispersion. This study aimed to functionally assess the parotid glands (PG) and submandibular glands (SMG) in a group of 40 healthy subjects using the novel Viscosity PLUS (Vi.PLUS) and 2D Shear-Wave Elastography PLUS (2D-SWE.PLUS) techniques. The viscosity and stiffness of PG and SMG were measured before and after gustatory stimulation with a sialagogue agent (commercially available lemon juice) using the new SuperSonic MACH 30 ultrasound system equipped with a curvilinear C6-1X transducer. PG presented a mean basal viscosity and elasticity of 2.10 ± 0.19 Pa.s and 11.32 ± 1.91 kPa, respectively, which significantly increased poststimulation to 2.39 ± 0.17 Pa.s (<i>p</i> < 0.001) and 12.58 ± 1.92 kPa (<i>p</i> < 0.001), respectively. SMG did not present statistically increased values of viscosity and elasticity following stimulation (2.31 ± 015 Pa.s vs. 2.37 ± 0.18 Pa.s, <i>p</i> = 0.086, and 10.40 ± 1.64 kPa vs. 10.90 ± 1.98 kPa, <i>p</i> = 0.074, respectively). Vi.PLUS measurements presented a good positive correlation with 2D-SWE.PLUS values for PG and SMG, before and after stimulation. Gender and BMI were not confounding factors for these two parameters. Vi.PLUS represents an innovative non-invasive imaging technique that, together with 2D-SWE.PLUS proves to be useful in functionally assessing the major salivary glands in healthy subjects.https://www.mdpi.com/2075-4418/12/8/1963salivary glandsshear-waveelastographyviscosityhealthy subjects |
| spellingShingle | Delia Doris Muntean Manuela Lavinia Lenghel Diana-Raluca Petea-Balea Anca Ileana Ciurea Carolina Solomon Sorin Marian Dudea Functional Evaluation of Major Salivary Glands Using Viscosity PLUS and 2D Shear-Wave PLUS Elastography Techniques in Healthy Subjects—A Pilot Study Diagnostics salivary glands shear-wave elastography viscosity healthy subjects |
| title | Functional Evaluation of Major Salivary Glands Using Viscosity PLUS and 2D Shear-Wave PLUS Elastography Techniques in Healthy Subjects—A Pilot Study |
| title_full | Functional Evaluation of Major Salivary Glands Using Viscosity PLUS and 2D Shear-Wave PLUS Elastography Techniques in Healthy Subjects—A Pilot Study |
| title_fullStr | Functional Evaluation of Major Salivary Glands Using Viscosity PLUS and 2D Shear-Wave PLUS Elastography Techniques in Healthy Subjects—A Pilot Study |
| title_full_unstemmed | Functional Evaluation of Major Salivary Glands Using Viscosity PLUS and 2D Shear-Wave PLUS Elastography Techniques in Healthy Subjects—A Pilot Study |
| title_short | Functional Evaluation of Major Salivary Glands Using Viscosity PLUS and 2D Shear-Wave PLUS Elastography Techniques in Healthy Subjects—A Pilot Study |
| title_sort | functional evaluation of major salivary glands using viscosity plus and 2d shear wave plus elastography techniques in healthy subjects a pilot study |
| topic | salivary glands shear-wave elastography viscosity healthy subjects |
| url | https://www.mdpi.com/2075-4418/12/8/1963 |
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