The bacterial strains isolated from trophic ulcers and their persistence factors
Background: Recently, a particular attention has been drawn to the study of the microbial persistence properties and their correlation with the rate of elimination from the source of infection, as well as the prognosis of the disease progression. Material and methods: There were examined 44 sample...
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| Format: | Article |
| Language: | English |
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Scientific Medical Association of Moldova
2019-12-01
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| Series: | The Moldovan Medical Journal |
| Subjects: | |
| Online Access: | http://moldmedjournal.md/wp-content/uploads/2019/12/moldovan-mej-j-2019-62-4-balan-full-text.pdf |
| _version_ | 1818144267533549568 |
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| author | Greta Balan |
| author_facet | Greta Balan |
| author_sort | Greta Balan |
| collection | DOAJ |
| description | Background: Recently, a particular attention has been drawn to the study of the microbial persistence properties and their correlation with the rate of
elimination from the source of infection, as well as the prognosis of the disease progression.
Material and methods: There were examined 44 samples taken from patients with trophic ulcers. The bacteriological examination, as well as tests on
determining both the persistence factors and the antibiotic susceptibility of the isolated strains were carried out according to the current method.
Results: There were determined 80 isolated bacterial strains. Two and more strains were isolated in over half of these cases (52.3%). The most commonly
involved strains were the genus Staphylococcus, followed by Enterobacter spp., Pseudomonas spp., Candida spp., and enterococci. Both gram-negative
and gram-positive species exhibited a high-level antimicrobial resistance. The study of the persistence factors revealed that the strains isolated in mixed
culture showed a higher rate of virulence (1.0-1.5 times higher) compared to isolates in pure culture.
Conclusions: The main bacterial strains isolated from trophic ulcers are the genus Staphylococcus and the Enterobacteriaceae family. Isolated strains
showed higher level of antimicrobial resistance and multiple persistence factors. The study results proved that treatment of trophic ulcers is still a major
problem, requiring rational monitoring and management strategies. |
| first_indexed | 2024-12-11T11:44:51Z |
| format | Article |
| id | doaj.art-42e5c4a4f4354904becfa3fc085b7ccb |
| institution | Directory Open Access Journal |
| issn | 2537-6373 2537-6381 |
| language | English |
| last_indexed | 2024-12-11T11:44:51Z |
| publishDate | 2019-12-01 |
| publisher | Scientific Medical Association of Moldova |
| record_format | Article |
| series | The Moldovan Medical Journal |
| spelling | doaj.art-42e5c4a4f4354904becfa3fc085b7ccb2022-12-22T01:08:30ZengScientific Medical Association of MoldovaThe Moldovan Medical Journal2537-63732537-63812019-12-01624363810.5281/zenodo.3556490The bacterial strains isolated from trophic ulcers and their persistence factorsGreta Balan0Department of Microbiology and Immunology, Nicolae Testemitsanu State University of Medicine and Pharmacy, Chisinau, the Republic of MoldovaBackground: Recently, a particular attention has been drawn to the study of the microbial persistence properties and their correlation with the rate of elimination from the source of infection, as well as the prognosis of the disease progression. Material and methods: There were examined 44 samples taken from patients with trophic ulcers. The bacteriological examination, as well as tests on determining both the persistence factors and the antibiotic susceptibility of the isolated strains were carried out according to the current method. Results: There were determined 80 isolated bacterial strains. Two and more strains were isolated in over half of these cases (52.3%). The most commonly involved strains were the genus Staphylococcus, followed by Enterobacter spp., Pseudomonas spp., Candida spp., and enterococci. Both gram-negative and gram-positive species exhibited a high-level antimicrobial resistance. The study of the persistence factors revealed that the strains isolated in mixed culture showed a higher rate of virulence (1.0-1.5 times higher) compared to isolates in pure culture. Conclusions: The main bacterial strains isolated from trophic ulcers are the genus Staphylococcus and the Enterobacteriaceae family. Isolated strains showed higher level of antimicrobial resistance and multiple persistence factors. The study results proved that treatment of trophic ulcers is still a major problem, requiring rational monitoring and management strategies.http://moldmedjournal.md/wp-content/uploads/2019/12/moldovan-mej-j-2019-62-4-balan-full-text.pdftrophic ulcersmicrobial spectrumantibiotic resistancepersistence factors |
| spellingShingle | Greta Balan The bacterial strains isolated from trophic ulcers and their persistence factors The Moldovan Medical Journal trophic ulcers microbial spectrum antibiotic resistance persistence factors |
| title | The bacterial strains isolated from trophic ulcers and their persistence factors |
| title_full | The bacterial strains isolated from trophic ulcers and their persistence factors |
| title_fullStr | The bacterial strains isolated from trophic ulcers and their persistence factors |
| title_full_unstemmed | The bacterial strains isolated from trophic ulcers and their persistence factors |
| title_short | The bacterial strains isolated from trophic ulcers and their persistence factors |
| title_sort | bacterial strains isolated from trophic ulcers and their persistence factors |
| topic | trophic ulcers microbial spectrum antibiotic resistance persistence factors |
| url | http://moldmedjournal.md/wp-content/uploads/2019/12/moldovan-mej-j-2019-62-4-balan-full-text.pdf |
| work_keys_str_mv | AT gretabalan thebacterialstrainsisolatedfromtrophiculcersandtheirpersistencefactors AT gretabalan bacterialstrainsisolatedfromtrophiculcersandtheirpersistencefactors |