Systematic Immunophenotyping Reveals Sex-Specific Responses After Painful Injury in Mice

Systematic Immunophenotyping Reveals Sex-Specific Responses After Painful Injury in Mice

Many diseases display unequal prevalence between sexes. The sex-specific immune response to both injury and persistent pain remains underexplored and would inform treatment paradigms. We utilized high-dimensional mass cytometry to perform a comprehensive analysis of phenotypic and functional immune...

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Bibliographic Details
Main Authors: Vivianne L. Tawfik, Nolan A. Huck, Quentin J. Baca, Edward A. Ganio, Elena S. Haight, Anthony Culos, Sajjad Ghaemi, Thanaphong Phongpreecha, Martin S. Angst, J. David Clark, Nima Aghaeepour, Brice Gaudilliere
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-07-01
Series:Frontiers in Immunology
Subjects:
mass cytometry
injury
inflammation
sex differences
pain
recovery
Online Access:https://www.frontiersin.org/article/10.3389/fimmu.2020.01652/full

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