Nox4 mediates skeletal muscle metabolic responses to exercise

Nox4 mediates skeletal muscle metabolic responses to exercise

Objective: The immediate signals that couple exercise to metabolic adaptations are incompletely understood. Nicotinamide adenine dinucleotide phosphate oxidase 4 (Nox4) produces reactive oxygen species (ROS) and plays a significant role in metabolic and vascular adaptation during stress conditions....

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Bibliographic Details
Main Authors: Kalyn S. Specht, Shashi Kant, Adele K. Addington, Ryan P. McMillan, Matthew W. Hulver, Heather Learnard, Maura Campbell, Sarah R. Donnelly, Amada D. Caliz, Yongmei Pei, Michaella M. Reif, Jacob M. Bond, Anthony DeMarco, Branch Craige, John F. Keaney, Jr., Siobhan M. Craige
Format: Article
Language:English
Published: Elsevier 2021-03-01
Series:Molecular Metabolism
Subjects:
Exercise
Nox4
ROS
Metabolic adaptation
Skeletal muscle metabolism
Endothelium
Online Access:http://www.sciencedirect.com/science/article/pii/S2212877820302349

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