Cyclic stretch enhances the expression of Toll-like Receptor 4 gene in cultured cardiomyocytes via p38 MAP kinase and NF-κB pathway

Cyclic stretch enhances the expression of Toll-like Receptor 4 gene in cultured cardiomyocytes via p38 MAP kinase and NF-κB pathway

<p>Abstract</p> <p>Background</p> <p>Toll-like receptor 4 (TLR4) plays an important role in innate immunity. The role of TLR4 in stretched cardiomyocytes is not known. We sought to investigate whether mechanical stretch could regulate TLR4 expression, as well as the pos...

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Bibliographic Details
Main Authors:	Wang Bao-Wei, Shyu Kou-Gi, Lin Chiu-Mei, Chang Hang
Format:	Article
Language:	English
Published:	BMC 2010-03-01
Series:	Journal of Biomedical Science
Online Access:	http://www.jbiomedsci.com/content/17/1/15

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