Complete Response to Immunotherapy Combined With Chemotherapy in a Patient With Gynecological Mixed Cancer Mainly Composed of Small Cell Neuroendocrine Carcinoma With High Tumor Mutational Burden: A Case Report

Complete Response to Immunotherapy Combined With Chemotherapy in a Patient With Gynecological Mixed Cancer Mainly Composed of Small Cell Neuroendocrine Carcinoma With High Tumor Mutational Burden: A Case Report

Small cell neuroendocrine carcinoma (SCNEC) is rare in the gynecologic tract, which has high invasive and metastatic ability. Due to the aggressive behavior and lack of treatment, patients have an extremely poor prognosis. Here we report a 66-year-old female diagnosed with SCNEC in the gynecologic t...

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Bibliographic Details
Main Authors: Xingyun Su, Xinhui Zhou, Cheng Xiao, Wei Peng, Qiangfeng Wang, Yulong Zheng
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-06-01
Series:Frontiers in Oncology
Subjects:
immune checkpoint inhibitor
gynecological tumor
small cell neuroendocrine carcinoma
tumor mutational burden
mixed cancer
Online Access:https://www.frontiersin.org/articles/10.3389/fonc.2022.750970/full

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