Myeloperoxidase Modulates Hydrogen Peroxide Mediated Cellular Damage in Murine Macrophages

Myeloperoxidase Modulates Hydrogen Peroxide Mediated Cellular Damage in Murine Macrophages

Myeloperoxidase (MPO) is involved in the development of many chronic inflammatory diseases, in addition to its key role in innate immune defenses. This is attributed to the excessive production of hypochlorous acid (HOCl) by MPO at inflammatory sites, which causes tissue damage. This has sparked wid...

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Bibliographic Details
Main Authors:	Chaorui Guo, Inga Sileikaite, Michael J. Davies, Clare L. Hawkins
Format:	Article
Language:	English
Published:	MDPI AG 2020-12-01
Series:	Antioxidants
Subjects:	hypochlorous acid hypothiocyanous acid thiocyanate glucose oxidase inflammation atherosclerosis
Online Access:	https://www.mdpi.com/2076-3921/9/12/1255

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