Profile and Correlates of Health-related Quality of Life in Chinese Patients with Coronary Heart Disease
Background: Although coronary heart disease (CHD) is one of the major cardiovascular diseases, risk factors associated with the health-related quality of life (HRQoL) of CHD patients remain unclear. The present study was designed to determine the profile and significant factors of the HRQoL in CHD p...
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| Format: | Article |
| Language: | English |
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Wolters Kluwer
2015-01-01
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| Series: | Chinese Medical Journal |
| Subjects: | |
| Online Access: | http://www.cmj.org/article.asp?issn=0366-6999;year=2015;volume=128;issue=14;spage=1853;epage=1861;aulast=Wang |
| _version_ | 1828846553801949184 |
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| author | Ling Wang Yi-Qun Wu Xun Tang Na Li Liu He Yang Cao Da-Fang Chen Yong-Hua Hu |
| author_facet | Ling Wang Yi-Qun Wu Xun Tang Na Li Liu He Yang Cao Da-Fang Chen Yong-Hua Hu |
| author_sort | Ling Wang |
| collection | DOAJ |
| description | Background: Although coronary heart disease (CHD) is one of the major cardiovascular diseases, risk factors associated with the health-related quality of life (HRQoL) of CHD patients remain unclear. The present study was designed to determine the profile and significant factors of the HRQoL in CHD patients.
Methods: A cross-sectional study was conducted in rural communities of Fangshan District, Beijing, China. Socio-demographic, lifestyle, and comorbidity information of CHD patients were collected by a structured questionnaire and medical records. HRQoL was measured using European Quality of Life 5-dimensions (EQ-5D) scale and EQ Visual Analog Scale (EQ-VAS). Multiple linear and logistic regressions were performed to explore the association of potential risk factors with HRQoL scores and each EQ-5D, respectively.
Results: Totally, 1928 CHD patients (mean age 61.64 ± 9.24 years; female:male = 2.4:1) were enrolled in the study. The mean score of EQ-5D index and EQ-VAS were 0.889 ± 0.172 and 71.56 ± 17.65, respectively. Multiple linear regression revealed that marital status, physical activity, moderate alcohol drinking, and family′s population were positive independent correlates of EQ-VAS, whereas diabetes mellitus and stroke were negative independent correlates (all P < 0.05). Age and stroke were negatively while physical activity, moderate alcohol drinking, family′s population and household income were positively correlated with EQ-5D index (all P < 0.05) independently. In addition, each of the five HRQoL dimensions had various specific determinants, including obesity, underweight, smoking or education.
Conclusions: Findings of the study highlight certain socio-demographic, lifestyle factors, and comorbid stroke or diabetes mellitus as correlates of HRQoL in Chinese CHD patients. Large-scale cohort studies should be carried out to confirm our results in the future. |
| first_indexed | 2024-12-12T21:51:17Z |
| format | Article |
| id | doaj.art-42eedb0549214cdbbb4a6318f36fd9d9 |
| institution | Directory Open Access Journal |
| issn | 0366-6999 |
| language | English |
| last_indexed | 2024-12-12T21:51:17Z |
| publishDate | 2015-01-01 |
| publisher | Wolters Kluwer |
| record_format | Article |
| series | Chinese Medical Journal |
| spelling | doaj.art-42eedb0549214cdbbb4a6318f36fd9d92022-12-22T00:10:47ZengWolters KluwerChinese Medical Journal0366-69992015-01-01128141853186110.4103/0366-6999.160486Profile and Correlates of Health-related Quality of Life in Chinese Patients with Coronary Heart DiseaseLing WangYi-Qun WuXun TangNa LiLiu HeYang CaoDa-Fang ChenYong-Hua HuBackground: Although coronary heart disease (CHD) is one of the major cardiovascular diseases, risk factors associated with the health-related quality of life (HRQoL) of CHD patients remain unclear. The present study was designed to determine the profile and significant factors of the HRQoL in CHD patients. Methods: A cross-sectional study was conducted in rural communities of Fangshan District, Beijing, China. Socio-demographic, lifestyle, and comorbidity information of CHD patients were collected by a structured questionnaire and medical records. HRQoL was measured using European Quality of Life 5-dimensions (EQ-5D) scale and EQ Visual Analog Scale (EQ-VAS). Multiple linear and logistic regressions were performed to explore the association of potential risk factors with HRQoL scores and each EQ-5D, respectively. Results: Totally, 1928 CHD patients (mean age 61.64 ± 9.24 years; female:male = 2.4:1) were enrolled in the study. The mean score of EQ-5D index and EQ-VAS were 0.889 ± 0.172 and 71.56 ± 17.65, respectively. Multiple linear regression revealed that marital status, physical activity, moderate alcohol drinking, and family′s population were positive independent correlates of EQ-VAS, whereas diabetes mellitus and stroke were negative independent correlates (all P < 0.05). Age and stroke were negatively while physical activity, moderate alcohol drinking, family′s population and household income were positively correlated with EQ-5D index (all P < 0.05) independently. In addition, each of the five HRQoL dimensions had various specific determinants, including obesity, underweight, smoking or education. Conclusions: Findings of the study highlight certain socio-demographic, lifestyle factors, and comorbid stroke or diabetes mellitus as correlates of HRQoL in Chinese CHD patients. Large-scale cohort studies should be carried out to confirm our results in the future.http://www.cmj.org/article.asp?issn=0366-6999;year=2015;volume=128;issue=14;spage=1853;epage=1861;aulast=WangCoronary Heart Disease; European Quality of Life 5-dimensions; Health-related Quality of Life; Risk Factor |
| spellingShingle | Ling Wang Yi-Qun Wu Xun Tang Na Li Liu He Yang Cao Da-Fang Chen Yong-Hua Hu Profile and Correlates of Health-related Quality of Life in Chinese Patients with Coronary Heart Disease Chinese Medical Journal Coronary Heart Disease; European Quality of Life 5-dimensions; Health-related Quality of Life; Risk Factor |
| title | Profile and Correlates of Health-related Quality of Life in Chinese Patients with Coronary Heart Disease |
| title_full | Profile and Correlates of Health-related Quality of Life in Chinese Patients with Coronary Heart Disease |
| title_fullStr | Profile and Correlates of Health-related Quality of Life in Chinese Patients with Coronary Heart Disease |
| title_full_unstemmed | Profile and Correlates of Health-related Quality of Life in Chinese Patients with Coronary Heart Disease |
| title_short | Profile and Correlates of Health-related Quality of Life in Chinese Patients with Coronary Heart Disease |
| title_sort | profile and correlates of health related quality of life in chinese patients with coronary heart disease |
| topic | Coronary Heart Disease; European Quality of Life 5-dimensions; Health-related Quality of Life; Risk Factor |
| url | http://www.cmj.org/article.asp?issn=0366-6999;year=2015;volume=128;issue=14;spage=1853;epage=1861;aulast=Wang |
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