Astragaloside IV Protects Ethanol-Induced Gastric Mucosal Injury by Preventing Mitochondrial Oxidative Stress and the Activation of Mitochondrial Pathway Apoptosis in Rats

Astragaloside IV Protects Ethanol-Induced Gastric Mucosal Injury by Preventing Mitochondrial Oxidative Stress and the Activation of Mitochondrial Pathway Apoptosis in Rats

Alcohol consumption affects gastric mucosa by multiple and complex mechanisms depending either by direct contact of ethanol or by indirect biological damage induced by its metabolite acetaldehyde. The present study aims at further investigating the mechanism of ethanol-induced gastric mucosa injury...

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Bibliographic Details
Main Authors: Shumin Qin, Jinjin Yin, Shaogang Huang, Jingyu Lin, Zhigang Fang, Yunsong Zhou, Keer Huang
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-08-01
Series:Frontiers in Pharmacology
Subjects:
astragaloside IV
mitochondrion
oxidative stress
apoptosis
ethanol
Online Access:https://www.frontiersin.org/article/10.3389/fphar.2019.00894/full

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